Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | TEAD1 | P28347 | 2/20 | 0.31 |
| ▸ | CNR1 | P21554 | 2/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6459954 | 1.00 | OPRM1 (0.35) | OPRM1OPRK1OPRL1DRD2ALDH1A1 | |
| SCHEMBL6451465 | 0.94 | DRD2 (0.33) | OPRM1OPRK1OPRL1DRD2IDO1 | |
| SCHEMBL6451469 | 0.94 | DRD2 (0.33) | OPRM1OPRK1OPRL1DRD2IDO1 | |
| SCHEMBL6453031 | 0.93 | DRD2 (0.32) | OPRM1OPRK1OPRL1DRD2MAPT | |
| SCHEMBL6453036 | 0.93 | DRD2 (0.32) | OPRM1OPRK1OPRL1DRD2MAPT | |
| SCHEMBL6458915 | 0.92 | GAA (0.33) | DRD2MAPTIDO1CNR1CNR2 | |
| SCHEMBL6455901 | 0.92 | GAA (0.33) | DRD2MAPTIDO1CNR1CNR2 | |
| SCHEMBL6455896 | 0.92 | GAA (0.33) | DRD2MAPTIDO1CNR1CNR2 | |
| SCHEMBL6458923 | 0.92 | GAA (0.33) | DRD2MAPTIDO1CNR1CNR2 | |
| SCHEMBL6457624 | 0.91 | IDO1 (0.33) | DRD2IDO1CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |