Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 5/20 | 0.59 |
| ▸ | NQO2 | P16083 | 1/20 | 0.59 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.57 |
| ▸ | NFE2L2 | Q16236 | 11/20 | 0.55 |
| ▸ | APP | P05067 | 3/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL918488 | 1.00 | PTGS1 (0.59) | PTGS1NQO2PTGS2NFE2L2APP | |
| SCHEMBL6469802 | 0.85 | PPARG (0.51) | PTGS1NQO2PTGS2 | |
| SCHEMBL918394 | 0.85 | PPARG (0.51) | PTGS1NQO2PTGS2 | |
| SCHEMBL919514 | 0.83 | PPARG (0.53) | PTGS1NQO2PTGS2NFE2L2APP | |
| SCHEMBL6469970 | 0.83 | PPARG (0.53) | PTGS1NQO2PTGS2NFE2L2APP | |
| SCHEMBL6468960 | 0.82 | AHR (0.54) | PTGS1PTGS2RELA | |
| SCHEMBL918449 | 0.82 | AHR (0.54) | PTGS1PTGS2RELA | |
| SCHEMBL6468964 | 0.82 | AHR (0.54) | PTGS1PTGS2RELA | |
| SCHEMBL919014 | 0.82 | NFE2L2 (0.46) | PTGS1NQO2PTGS2NFE2L2 | |
| SCHEMBL6471008 | 0.79 | PTGS1 (0.58) | PTGS1PTGS2NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1554236-A1 | NOVEL BIOACTIVE DIPHENYL ETHENE COMPOUNDS AND THEIR THERAPEUTIC APPLICATIONS | Welichem Biotech Inc. (CA) | 2005-07-20 | — | — | EP | claimed |
| WO-2004031117-A1 | NOVEL BIOACTIVE DIPHENYL ETHENE COMPOUNDS AND THEIR THERAPEUTIC APPLICATIONS | WELICHEM BIOTECH INC. (CA) | 2004-04-15 | — | — | WO | claimed |
| EP-1554236-A1 | NOVEL BIOACTIVE DIPHENYL ETHENE COMPOUNDS AND THEIR THERAPEUTIC APPLICATIONS | Welichem Biotech Inc. (CA) | 2005-07-20 | — | — | EP | disclosed |
| WO-2004031117-A1 | NOVEL BIOACTIVE DIPHENYL ETHENE COMPOUNDS AND THEIR THERAPEUTIC APPLICATIONS | WELICHEM BIOTECH INC. (CA) | 2004-04-15 | — | — | WO | disclosed |