Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Styrene SCHEMBL5670947 | 0.98 | ALDH1A1 (0.61) | ALDH1A1TSHRTP53TDP1RELA | |
| Styrene SCHEMBL2862346 | 0.91 | ALDH1A1 (0.78) | ALDH1A1TSHRTP53TDP1RELA | |
| Styrene SCHEMBL28064670 | 0.91 | ALDH1A1 (0.78) | ALDH1A1TSHRTP53TDP1HDAC8 | |
| Styrene SCHEMBL7904441 | 0.91 | ALDH1A1 (0.78) | ALDH1A1TSHRTP53TDP1HDAC8 | |
| Styrene SCHEMBL27316735 | 0.91 | ALDH1A1 (0.78) | ALDH1A1TSHRTP53TDP1HDAC8 | |
| Styrene SCHEMBL15656 | 0.91 | ALDH1A1 (0.78) | ALDH1A1TSHRTP53TDP1HDAC8 | |
| Styrene SCHEMBL27670945 | 0.90 | ALDH1A1 (0.52) | ALDH1A1TSHRTP53TDP1RELA | |
| Styrene SCHEMBL28238242 | 0.88 | ALDH1A1 (0.67) | ALDH1A1TSHRTP53TDP1HDAC8 | |
| Styrene SCHEMBL28019103 | 0.88 | ALDH1A1 (0.74) | ALDH1A1TSHRTP53TDP1RELA | |
| Styrene SCHEMBL27910207 | 0.88 | ALDH1A1 (0.74) | ALDH1A1TSHRTP53TDP1RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1036319-B1 | PROCESS FOR OBTAINING L-DIHYDROOROTIC ACID AND USE THEREOF | AVENTIS PHARMA GMBH (DE) | 2005-09-28 | — | — | EP | disclosed |
| CN-1111171-C | Heparin and its preparing process | HUIHAI BIOCHEMICAL PRODUCTS FA (CN) | 2003-06-11 | — | — | CN | disclosed |
| US-6545006-B1 | High pressure chromatography on an anionic exchange material; determining the activity of a dihydroorotic acid dehydrogenase inhibitor; diagnostic assay | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2003-04-08 | — | — | US | disclosed |
| CN-1272457-A | New method for treating industrial raw water by using deaerization and softening process | HUO YINKUN (CN) | 2000-11-08 | — | — | CN | disclosed |
| EP-1036319-A1 | PROCESS FOR OBTAINING L-DIHYDROOROTIC ACID AND USE THEREOF | Aventis Pharma Deutschland GmbH (DE) | 2000-09-20 | — | — | EP | disclosed |
| EP-0933633-A1 | Process for obtaining L-dihydroorotic acid and use thereof | Hoechst Marion Roussel Deutschland GmbH (DE) | 1999-08-04 | — | — | EP | disclosed |
| WO-1999030146-A1 | PROCESS FOR OBTAINING L-DIHYDROOROTIC ACID AND USE THEREOF | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 1999-06-17 | — | — | WO | disclosed |