Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV3 | Q8NET8 | 2/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6458709 | 1.00 | TRPV3 (0.32) | TRPV3SLC6A2SLC6A4SLC6A3GRM5 | |
| SCHEMBL6452254 | 0.91 | CYP2C9 (0.36) | GRM5 | |
| SCHEMBL6452259 | 0.91 | CYP2C9 (0.36) | GRM5 | |
| SCHEMBL6453256 | 0.90 | SLC6A2 (0.32) | TRPV3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6453262 | 0.90 | SLC6A2 (0.32) | TRPV3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6456344 | 0.89 | RAB9A (0.32) | — | |
| SCHEMBL6456338 | 0.89 | RAB9A (0.32) | — | |
| SCHEMBL6454998 | 0.88 | RAB9A (0.31) | — | |
| SCHEMBL6454996 | 0.88 | RAB9A (0.31) | — | |
| SCHEMBL6452319 | 0.87 | SLC6A2 (0.37) | TRPV3SLC6A2SLC6A4SLC6A3GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |