SCHEMBL6460976

SCHEMBL6460976

CC=[Zr](C)(Cl)(Cl)(C1C(CC)=Cc2c(-c3ccc(C(C)(C)C)cc3)cccc21)C1C(CC)=Cc2c(-c3ccc(C(C)(C)C)cc3)cccc21

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
NR1H4 Q96RI1 2/20 0.31
BRD4 O60885 1/20 0.31
CREBBP Q92793 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7170563 0.77 BRD4 (0.32) BRD4CREBBP
SCHEMBL5358431 0.77
SCHEMBL5352780 0.76
SCHEMBL6890535 0.76 BRD4 (0.35) BRD4CREBBP
SCHEMBL7783132 0.76 BRD4 (0.35) BRD4CREBBP
SCHEMBL7198398 0.76 BRD4 (0.35) BRD4CREBBP
SCHEMBL7035276 0.76 BRD4 (0.33) BRD4CREBBP
SCHEMBL7035813 0.76 BRD4 (0.33) BRD4CREBBP
SCHEMBL139250 0.76
SCHEMBL7182715 0.76 BRD4 (0.30) BRD4CREBBP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6900343-B1 Method for the purification of metallocenes BASELL POLYOLEFINE GMBH (DE) 2005-05-31 US disclosed
US-6861384-B2 Process for preparation of a salt-like chemical compound and its use in catalyst systems for preparing polyolefins BASELL POLYOLEFINE GMBH (DE) 2005-03-01 US disclosed
US-20040072975-A1 Salt-like chemical compound, its preparation and its use in catalyst systems for preparing polyolefins BASELL POLYPROPYLEN GMBH (DE) 2004-04-15 US disclosed
US-20040048992-A1 Process for preparation of salt-like chemical compound, and its use in catalyst systems for preparing polyolefins EQUISTAR CHEMICALS, LP 2004-03-11 US disclosed
US-20030144434-A1 Chemical products suited for use as co-catalysts, method for the preparation thereof and their use in catalyst systems for producing polyolefins EQUISTAR CHEMICALS, LP 2003-07-31 US disclosed
US-20030109652-A1 Catalyst system BOHNEN HANS (DE) 2003-06-12 US disclosed
US-20030069426-A1 Saline chemical composition, method for producing the same and the use thereof in catalyst systems for producing polyolefins SCHOTTEK JORG (DE) 2003-04-10 US disclosed
US-20030013913-A1 Chemical compound, method for the production thereof and its use in catalyst systems for producing polyolefins EQUISTAR CHEMICALS, LP 2003-01-16 US disclosed
US-20030008984-A1 Novel catalyst system and the use thereof BASELL POLYOLEFINE GMBH (DE) 2003-01-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030144434-A1 Chemical products suited for use as co-catalysts, method for the preparation thereof and their use in catalyst systems for producing polyolefins CBR1, COX6C, CBR3 NR1H4 1133/4885BRD4 3253/4885CREBBP 4652/4885
US-20030069426-A1 Saline chemical composition, method for producing the same and the use thereof in catalyst systems for producing polyolefins CLIC1, HACL2, ADH1C NR1H4 2447/4885BRD4 2173/4885CREBBP 3075/4885
US-20030013913-A1 Chemical compound, method for the production thereof and its use in catalyst systems for producing polyolefins SCO2, CNOT1, CYC1 NR1H4 1273/4885BRD4 1774/4885CREBBP 3332/4885
US-20040048992-A1 Process for preparation of salt-like chemical compound, and its use in catalyst systems for preparing polyolefins CLIC1, HACL2, RFC1 NR1H4 2737/4885BRD4 1535/4885CREBBP 2517/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.