SCHEMBL6461210

SCHEMBL6461210

CCCCCCCCc1cccc(OP(Oc2cccc(CCCCCCCC)c2CCCCCCCC)Oc2cccc(CCCCCCCC)c2CCCCCCCC)c1CCCCCCCC

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 5/20 0.50
ALOX5 P09917 1/20 0.50
PPARA Q07869 3/20 0.48
THRA P10827 1/20 0.47
THRB P10828 1/20 0.47
PPARG P37231 2/20 0.46
LIPG Q9Y5X9 1/20 0.44
LTB4R Q15722 1/20 0.43
LTB4R2 Q9NPC1 1/20 0.43
BID P55957 3/20 0.41
MCL1 Q07820 3/20 0.41
BCL2L1 Q07817 2/20 0.41
BAK1 Q16611 2/20 0.41
KAT8 Q9H7Z6 2/20 0.41
EP300 Q09472 1/20 0.41
KAT2A Q92830 1/20 0.41
KAT2B Q92831 1/20 0.41
KAT5 Q92993 1/20 0.41
SAE1 Q9UBE0 1/20 0.41
SLC2A1 P11166 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31357419 1.00 PTGS2 (0.50) PTGS2ALOX5PPARATHRATHRB
SCHEMBL8389827 1.00 PTGS2 (0.50) PTGS2ALOX5PPARATHRATHRB
SCHEMBL6520493 1.00 PTGS2 (0.50) PTGS2ALOX5PPARATHRATHRB
SCHEMBL9339451 1.00 PTGS2 (0.50) PTGS2ALOX5PPARATHRATHRB
SCHEMBL5490287 1.00 PTGS2 (0.50) PTGS2ALOX5PPARATHRATHRB
SCHEMBL94595 1.00 PTGS2 (0.50) PTGS2ALOX5PPARATHRATHRB
SCHEMBL160365 0.98 PTGS2 (0.51) PTGS2ALOX5PPARATHRATHRB
SCHEMBL11173065 0.97 THRA (0.51) PTGS2ALOX5PPARATHRATHRB
SCHEMBL8379300 0.97 THRA (0.51) PTGS2ALOX5PPARATHRATHRB
SCHEMBL2350501 0.97 THRA (0.51) PTGS2ALOX5PPARATHRATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4394472-A ARYL PHOSPHITE AND TRIAZINE COMPOUND JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1983-07-19 US claimed
CN-107793512-B (meth) acrylate-styrene copolymer, composition thereof, and molded article 奇美实业股份有限公司 2020-07-14 CN disclosed
CN-110845807-A Rubber modified resin composition and molded article produced from the same 奇美实业股份有限公司 2020-02-28 CN disclosed
US-6887926-B1 Bonding compositions for chlorinated polymers and methods of using the same OATEY CO. (US) 2005-05-03 US disclosed
EP-1303564-B1 STABILISER SYSTEM COMPRISING HYDROXYACIDS AKZO NOBEL NV (NL) 2004-03-10 EP disclosed
EP-0826016-B1 STABILISED VINYL CHLORIDE POLYMER COMPOSITIONS AKCROS CHEM (GB) 2003-10-22 EP disclosed
EP-0734414-B2 STABILISED VINYL CHLORIDE COMPOSITION AKCROS CHEM (GB) 2003-10-22 EP disclosed
EP-1303564-A2 STABILISER SYSTEM COMPRISING HYDROXYACIDS Akzo Nobel N.V. (NL) 2003-04-23 EP disclosed
US-20020032259-A1 Stabliser system comprising hydroxyacids AKZO NOBEL N.V. (NL) 2002-03-14 US disclosed
WO-2002006389-A2 STABILISER SYSTEM COMPRISING HYDROXYACIDS AKZO NOBEL N.V. (NL) 2002-01-24 WO disclosed
WO-1995016739-A1 STABILISED VINYL CHLORIDE COMPOSITION AKCROS CHEMICALS (GB) 1995-06-22 WO disclosed
US-5049292-A Alkylbenzene, polyolefin, phosphate or phosphite, silicone TEXACO TECHNOLOGIE EUROPA GMBH (DE) 1991-09-17 US disclosed
US-4950704-A DIKETONE AS HEAT STABILIZER ARGUS CHEMICAL CORPORATION (US) 1990-08-21 US disclosed
EP-0331095-A1 Improving stability at moderate temperatures of motor vehicle components shaped from polyvinyl chloride resin compositions WITCO CORPORATION (US) 1989-09-06 EP disclosed
US-4394472-A ARYL PHOSPHITE AND TRIAZINE COMPOUND JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1983-07-19 US disclosed
US-4209431-A OXIDATION AND HEAT RESISTANCE WITCO CHEMICAL CORPORATION (US) 1980-06-24 US disclosed
US-4105627-A MERCAPTOHETEROCYCLIC RESIN STABILIZERS ARGUS CHEMICAL CORPORATION (US) 1978-08-08 US disclosed
US-4080364-A Stabilization of polyolefins against degradative deterioration as a result of exposure to light and air at elevated temperatures ARGUS CHEMICAL CORPORATION (US) 1978-03-21 US disclosed
US-3997551-A OXIDATION RESISTANCE, STABILIZE POLYMERS ARGUS CHEMICAL CORPORATION (US) 1976-12-14 US disclosed
US-3948801-A Stabilizer composition of phosphite and lignin WESTVACO CORPORATION (US) 1976-04-06 US disclosed