SCHEMBL64613

SCHEMBL64613

COC(=N)c1ccccn1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.50
CES2 O00748 1/20 0.48
CES1 P23141 1/20 0.48
SMN1; SMN2 Q16637 7/20 0.47
NPC1 O15118 5/20 0.47
RAB9A P51151 5/20 0.47
MAPT P10636 4/20 0.47
PKM P14618 4/20 0.47
KDM4E B2RXH2 6/20 0.47
LMNA P02545 2/20 0.47
NAPRT Q6XQN6 1/20 0.47
P4HTM Q9NXG6 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
POLB P06746 1/20 0.46
HPGD P15428 2/20 0.45
CDK5 Q00535 1/20 0.45
PAX8 Q06710 1/20 0.45
CDK5R1 Q15078 1/20 0.45
GRM4 Q14833 3/20 0.44
HTT P42858 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19668773 0.79 ALDH1A1 (0.46) ALDH1A1CES2CES1SMN1; SMN2NPC1
SCHEMBL504660 0.79 ALDH1A1 (0.46) ALDH1A1CES2CES1SMN1; SMN2NPC1
SCHEMBL5640995 0.78 ALDH1A1 (0.54) ALDH1A1CES2CES1SMN1; SMN2NPC1
Hydrochloric Acid SCHEMBL4430965 0.77 KDM4E (0.44) ALDH1A1CES2CES1SMN1; SMN2NPC1
Hydrochloric Acid SCHEMBL5450983 0.77 KDM4E (0.44) ALDH1A1CES2CES1SMN1; SMN2NPC1
SCHEMBL4378933 0.77 ALDH1A1 (0.57) ALDH1A1CES2CES1SMN1; SMN2NPC1
SCHEMBL22653498 0.76 ALDH1A1 (0.43) ALDH1A1CES2CES1SMN1; SMN2NPC1
SCHEMBL30314230 0.76 ALDH1A1 (0.43) ALDH1A1CES2CES1SMN1; SMN2NPC1
SCHEMBL14114235 0.76 MEN1 (0.42) ALDH1A1SMN1; SMN2NPC1RAB9AMAPT
SCHEMBL6006624 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5062 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025078932-A1 A PROCESS FOR SELECTIVE DIMETHYL CARBONATE (DMC) SYNTHESIS AND A SYSTEM THEREOF RELIANCE INDUSTRIES LIMITED (IN) 2025-04-17 WO claimed
WO-2025078933-A1 A PROCESS FOR SELECTIVE DIMETHYL CARBONATE (DMC) SYNTHESIS AND A SYSTEM THEREOF RELIANCE INDUSTRIES LIMITED (IN) 2025-04-17 WO claimed
EP-1797123-B1 COMPLEMENTARY PEPTIDES FOR ß-AMYLOID 29-42 PEPTIDE UNIV LIEGE (BE) 2010-03-03 EP claimed
EP-4748862-A2 HETERODIMERIC PROTEINS Xencor, Inc. (US) 2026-05-27 EP disclosed
EP-3620473-B1 NOVEL HETERODIMERIC PROTEINS XENCOR INC (US) 2026-05-27 EP disclosed
EP-3865514-B9 BISPECIFIC ANTIBODY BINDING DLL3 AND CD3 AMGEN RES MUNICH GMBH (DE) 2026-05-20 EP disclosed
US-12630650-B2 Engineered IgA antibodies and methods of use TIGATX, INC. (US) 2026-05-19 US disclosed
US-20260132199-A1 ANTIBODY CONSTRUCTS FOR DLL3 AND CD3 AMGEN RES MUNICH GMBH (DE) 2026-05-14 US disclosed
EP-4741424-A2 FC VARIANTS WITH ALTERED BINDING TO FCRN Xencor, Inc. (US) 2026-05-13 EP disclosed
EP-3817770-B1 ANTI-STEAP1 ANTIGEN-BINDING PROTEIN AMGEN INC (US) 2026-05-06 EP disclosed
US-12617853-B2 Low pH pharmaceutical composition comprising T cell engaging antibody constructs Amgen Research (Munich), GmbH (DE) 2026-05-05 US disclosed
EP-0072121-A1 Beta-lactam antibiotics BEECHAM GROUP PLC (GB) 1983-02-16 EP disclosed
US-4335043-A Substituted N-methylene derivatives of thienamycin MERCK & CO., INC. (US) 1982-06-15 US disclosed
US-4232030-A ANTIBIOTICS MERCK & CO., INC. (US) 1980-11-04 US disclosed
US-4194047-A Substituted N-methylene derivatives of thienamycin MERCK & CO., INC. (US) 1980-03-18 US disclosed
EP-0001264-A1 Substituted N-methylene derivatives of thienamycin sulfoxide and sulfone and their preparation MERCK & CO. INC. (US) 1979-04-04 EP disclosed
US-4073783-A PENICILLINS PFIZER INC. (US) 1978-02-14 US disclosed
US-4025506-A PENICILLINS PFIZER INC. (US) 1977-05-24 US disclosed
US-4025504-A PENICILLINS PFIZER INC. (US) 1977-05-24 US disclosed
US-3951952-A 6-(ALPHA-(AMIDINO-AND IMIDOYLAMINOALKANOYLAMINO)ARACYLAMINO)-PENICILLANIC ACIDS PFIZER INC. (US) 1976-04-20 US disclosed