Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.42 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4430965 | 0.98 | KDM4E (0.44) | ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL5450983 | 0.98 | KDM4E (0.44) | ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL15301296 | 0.93 | ALDH1A1 (0.41) | ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL30314230 | 0.86 | ALDH1A1 (0.43) | ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL22653498 | 0.86 | ALDH1A1 (0.43) | ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL4380607 | 0.79 | ALDH1A1 (0.47) | ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL29809810 | 0.79 | ALDH1A1 (0.47) | ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL64613 | 0.79 | ALDH1A1 (0.50) | ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A | |
| Ethyl Picolinate SCHEMBL126181 | 0.78 | CYP1A2 (0.65) | ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A | |
| Ethyl Picolinate SCHEMBL30016787 | 0.78 | CYP1A2 (0.65) | ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023091726-A1 | INHIBITORS OF CYCLIN‑DEPENDENT KINASE 12 (CDK12) | SYROS PHARMACEUTICALS, INC. (US) | 2023-05-25 | — | — | WO | disclosed |
| US-11634391-B2 | Compounds which are inhibitors of Notum | UCL BUSINESS LTD (GB) | 2023-04-25 | — | — | US | disclosed |
| EP-3843844-A1 | COMPOUNDS | UCL Business Ltd (GB) | 2021-07-07 | — | — | EP | disclosed |
| US-20210171475-A1 | COMPOUNDS | UCL BUSINESS LTD (GB) | 2021-06-10 | — | — | US | disclosed |
| US-20210171475-A1 | COMPOUNDS | UCL BUSINESS LTD (GB) | 2021-06-10 | — | — | US | disclosed |
| CN-109867623-B | 3-pyridyl-3-amino-2-cyanoacrylate compounds and preparation method and application thereof | 江苏省农药研究所股份有限公司 | 2021-02-09 | — | — | CN | disclosed |
| WO-2020043866-A1 | COMPOUNDS | UCL BUSINESS LTD (GB) | 2020-03-05 | — | — | WO | disclosed |
| WO-2020043866-A1 | COMPOUNDS | UCL BUSINESS LTD (GB) | 2020-03-05 | — | — | WO | disclosed |
| EP-2609236-A1 | PEPTIDE LIBRARIES FOR SCREENING AND OTHER APPLICATIONS | Agency For Science, Technology And Research (SG) | 2013-07-03 | — | — | EP | disclosed |
| WO-2012026887-A1 | PEPTIDE LIBRARIES FOR SCREENING AND OTHER APPLICATIONS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2012-03-01 | — | — | WO | disclosed |
| US-20040011252-A1 | Non-toxic corrosion-protection pigments based on manganese | UNIVERSITY OF DAYTON | 2004-01-22 | — | — | US | disclosed |
| US-20030234063-A1 | Non-toxic corrosion-protection conversion coats based on cobalt | DAYTON, UNIVERSITY OF | 2003-12-25 | — | — | US | disclosed |
| US-20030230363-A1 | Non-toxic corrosion-protection rinses and seals based on cobalt | UNIVERSITY OF DAYTON | 2003-12-18 | — | — | US | disclosed |
| WO-2003060191-A2 | NON-TOXIC CORROSION-PROTECTION CONVERSION COATINGES ABSED ON COBALT | UNIVERSITY OF DAYTON (US) | 2003-07-24 | — | — | WO | disclosed |
| WO-2003060192-A1 | NON-TOXIC CORROSION-PROTECTION RINSES AND SEALS BASED ON COBALT | UNIVERSITY OF DAYTON (US) | 2003-07-24 | — | — | WO | disclosed |
| WO-2003060019-A1 | NON-TOXIC CORROSION PROTECTION PIGMENTS BASED ON COBALT | UNIVERSITY OF DAYTON (US) | 2003-07-24 | — | — | WO | disclosed |
| US-5436338-A | Aromatic amidine compounds for radiation resistance | GIVAUDAN-ROURE CORPORATION (US) | 1995-07-25 | — | — | US | disclosed |
| US-5243055-A | Photostability | GIVAUDAN CORPORATION (US) | 1993-09-07 | — | — | US | disclosed |
| EP-0491280-A1 | Formamidines useful as ultraviolet light absorbers | GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) | 1992-06-24 | — | — | EP | disclosed |
| US-4788210-A | PESTICIDES | HOFFMANN-LA ROCHE INC. (US) | 1988-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11634391-B2 | Compounds which are inhibitors of Notum | NOTUM, GOT2, GOT1 | ALDH1A1 1260/4885KDM4E 3907/4885SMN1; SMN2 451/4885 |
| US-20210171475-A1 | COMPOUNDS | GOT2, GOT1, OAT | ALDH1A1 658/4885KDM4E 4149/4885SMN1; SMN2 74/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.