Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6461467 | 1.00 | LSS (0.40) | LSSSIGMAR1MCL1HDAC3MAPK1 | |
| SCHEMBL9763000 | 0.80 | LSS (0.44) | LSSSIGMAR1HDAC3MAPK1ADRA1A | |
| SCHEMBL9763004 | 0.80 | LSS (0.44) | LSSSIGMAR1HDAC3MAPK1ADRA1A | |
| SCHEMBL6258245 | 0.77 | TRPV1 (0.49) | SIGMAR1HDAC3MAPK1ADRA1AHDAC4 | |
| SCHEMBL13393571 | 0.74 | LSS (0.52) | LSSSIGMAR1HDAC3MAPK1ADRA1A | |
| SCHEMBL4667862 | 0.71 | HDAC3 (0.48) | HDAC3MAPK1ADRA1AHDAC4SLC6A3 | |
| SCHEMBL443151 | 0.71 | HDAC3 (0.48) | HDAC3MAPK1ADRA1AHDAC4SLC6A3 | |
| SCHEMBL1574137 | 0.71 | HDAC3 (0.48) | HDAC3MAPK1ADRA1AHDAC4SLC6A3 | |
| SCHEMBL17732044 | 0.71 | HDAC1 (0.44) | SIGMAR1HDAC3MAPK1ADRA1AHDAC4 | |
| SCHEMBL8624953 | 0.71 | LSS (0.49) | LSSHDAC3MAPK1ADRA1AHDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050148492-A1 | Fragrance compounds | QUEST INTERNATIONAL B.V. (NL) | 2005-07-07 | — | — | US | disclosed |
| EP-1353901-A1 | FRAGRANCE COMPOUNDS | QUEST INTERNATIONAL B.V. (NL) | 2003-10-22 | — | — | EP | disclosed |
| WO-2002059079-A1 | FRAGRANCE COMPOUNDS | QUEST INTERNATIONAL B.V. (NL) | 2002-08-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050148492-A1 | Fragrance compounds | NISCH, HRH1, TRPA1 | LSS 451/4885SIGMAR1 109/4885MCL1 3241/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.