Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ACE | P12821 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL16766056 | 0.99 | CYP3A4 (0.47) | CYP3A4KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL5954481 | 0.97 | CYP3A4 (0.48) | CYP3A4KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL4399111 | 0.97 | CYP3A4 (0.48) | CYP3A4KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL4616899 | 0.97 | CYP3A4 (0.48) | CYP3A4KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL4399114 | 0.97 | CYP3A4 (0.48) | CYP3A4KMT2AKDM4EALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL5593751 | 0.96 | ACE (0.49) | CYP3A4KMT2AKDM4EALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL5793334 | 0.96 | ACE (0.49) | CYP3A4KMT2AKDM4EALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL4616123 | 0.96 | ACE (0.49) | CYP3A4KMT2AKDM4EALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL5791761 | 0.96 | ACE (0.49) | CYP3A4KMT2AKDM4EALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL5549564 | 0.96 | ACE (0.49) | CYP3A4KMT2AKDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8119375-B2 | Method for the production of ramipril | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2012-02-21 | — | — | US | disclosed |
| US-20090017509-A1 | METHOD FOR THE PRODUCTION OF RAMIPRIL | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2009-01-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090017509-A1 | METHOD FOR THE PRODUCTION OF RAMIPRIL | REN, PDE8B, PDE3A | CYP3A4 37/4885KMT2A 2722/4885KDM4E 2521/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.