Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.33 |
| ▸ | TACR2 | P21452 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SHBG | P04278 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methane SCHEMBL28205579 | 0.98 | PTGS2 (0.33) | PTGS2CYP3A4ESR1ADRA2AADORA3 | |
| SCHEMBL27832533 | 0.98 | PTGS2 (0.36) | PTGS2CYP3A4ESR1ADRA2AADORA3 | |
| SCHEMBL9149230 | 0.98 | PTGS2 (0.36) | PTGS2CYP3A4ESR1ADRA2AADORA3 | |
| SCHEMBL1539757 | 0.98 | PTGS2 (0.36) | PTGS2CYP3A4ESR1ADRA2AADORA3 | |
| SCHEMBL2589165 | 0.98 | PTGS2 (0.36) | PTGS2CYP3A4ESR1ADRA2AADORA3 | |
| SCHEMBL2589979 | 0.98 | PTGS2 (0.36) | PTGS2CYP3A4ESR1ADRA2AADORA3 | |
| SCHEMBL18166883 | 0.98 | PTGS2 (0.36) | PTGS2CYP3A4ESR1ADRA2AADORA3 | |
| SCHEMBL2589096 | 0.98 | PTGS2 (0.36) | PTGS2CYP3A4ESR1ADRA2AADORA3 | |
| SCHEMBL2581422 | 0.98 | PTGS2 (0.36) | PTGS2CYP3A4ESR1ADRA2AADORA3 | |
| SCHEMBL2586965 | 0.98 | PTGS2 (0.36) | PTGS2CYP3A4ESR1ADRA2AADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104685650-B | The salt of the cyclopentadiene of n-type dopant as organic electronic device | 西门子公司 | 2018-03-27 | — | — | CN | claimed |
| US-8975427-B2 | Synthesis of alkyl cyclopentadiene compounds | UNIVATION TECHNOLOGIES, LLC (US) | 2015-03-10 | — | — | US | claimed |
| US-20130085289-A1 | Synthesis of Alkyl Cyclopentadiene Compounds | UNIVATION TECHNOLOGIES, LLC (US) | 2013-04-04 | — | — | US | claimed |
| EP-2563747-A1 | SYNTHESIS OF ALKYL CYCLOPENTADIENE COMPOUNDS | Univation Technologies, LLC (US) | 2013-03-06 | — | — | EP | claimed |
| CN-102844284-A | Synthesis method of alkyl cyclopentadiene compound | UNIVATION TECH LLC | 2012-12-26 | — | — | CN | claimed |
| WO-2011136902-A1 | SYNTHESIS OF ALKYL CYCLOPENTADIENE COMPOUNDS | UNIVATION TECHNOLOGIES, LLC (US) | 2011-11-03 | — | — | WO | claimed |
| EP-0621963-B1 | VISIBLE AND ULTRAVIOLET IRRADIATION PHOTOSENSITIVE SYSTEM FOR FILM-FORMING PIGMENTED PHOTO-CROSSLINKABLE COMPOSITIONS | CELLIOSE (FR) | 1999-09-22 | — | — | EP | claimed |
| EP-0621963-A1 | VISIBLE AND ULTRAVIOLET IRRADIATION PHOTOSENSITIVE SYSTEM FOR FILM-FORMING PIGMENTED PHOTO-CROSSLINKABLE COMPOSITIONS | CELLIOSE (FR) | 1994-11-02 | — | — | EP | claimed |
| WO-1993015440-A1 | VISIBLE AND ULTRAVIOLET IRRADIATION PHOTOSENSITIVE SYSTEM FOR FILM-FORMING PIGMENTED PHOTO-CROSSLINKABLE COMPOSITIONS | CELLIOSE (FR) | 1993-08-05 | — | — | WO | claimed |
| EP-0325617-A1 | THIOLENE COMPOSITIONS BASED ON BICYCLIC 'ENE COMPOUNDS. | LOCTITE CORP (US) | 1989-08-02 | — | — | EP | claimed |
| US-4808638-A | CROSSLINKING WITH POLYMERCAPTANS | LOCTITE CORPORATION (US) | 1989-02-28 | — | — | US | claimed |
| WO-1988002902-A2 | THIOLENE COMPOSITIONS BASED ON BICYCLIC 'ENE COMPOUNDS | LOCTITE CORPORATION (US) | 1988-04-21 | — | — | WO | claimed |
| US-4329508-A | Process for making alkyl cyclopentenones | SCM CORPORATION (US) | 1982-05-11 | — | — | US | claimed |
| US-10870618-B2 | Histone deacetylase inhibitors and uses thereof | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) | 2020-12-22 | — | — | US | disclosed |
| EP-3177630-B1 | SILYLATION OF AROMATIC HETEROCYCLES BY EARTH ABUNDANT TRANSITION-METAL-FREE CATALYSTS | CALIFORNIA INST OF TECHN (US) | 2019-10-23 | — | — | EP | disclosed |
| US-20190308932-A1 | HISTONE DEACETYLASE INHIBITORS AND USES THEREOF | MEDICAL UNIVERSITY OF SOUTH CAROLINA | 2019-10-10 | — | — | US | disclosed |
| US-4329508-A | Process for making alkyl cyclopentenones | SCM CORPORATION (US) | 1982-05-11 | — | — | US | disclosed |
| US-4173517-A | Electrochemical process for dicyclopentadienyl iron | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 1979-11-06 | — | — | US | disclosed |
| US-4127497-A | Michael adducts of (substituted) cyclopentadiene and esters: a process therefor and derivatives thereof | THE DOW CHEMICAL COMPANY (US) | 1978-11-28 | — | — | US | disclosed |
| US-3962182-A | CHROMIUMIII CARBOXYLATE CATALYST | AEROJET-GENERAL CORPORATION (US) | 1976-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10870618-B2 | Histone deacetylase inhibitors and uses thereof | HDAC1, HDAC5, HDAC3 | PTGS2 3794/4885CYP3A4 3024/4885ESR1 4223/4885 |
| US-20190308932-A1 | HISTONE DEACETYLASE INHIBITORS AND USES THEREOF | HDAC1, HDAC5, HDAC3 | PTGS2 3794/4885CYP3A4 3024/4885ESR1 4223/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.