Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | CHRM5 | P08912 | 5/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.42 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.42 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.42 |
| ▸ | GALR3 | O60755 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3457975 | 0.90 | THRB (0.46) | THRBCHRM5CHRM1CHRM3CHRM2 | |
| SCHEMBL258945 | 0.88 | THRB (0.47) | THRBCHRM5CHRM1CHRM3CHRM2 | |
| Phosphoric Acid SCHEMBL9619842 | 0.88 | CHRM5 (0.53) | THRBCHRM5CHRM1CHRM3CHRM2 | |
| Triethyl Phosphate SCHEMBL7896685 | 0.87 | CHRM5 (0.49) | THRBCHRM5CHRM1CHRM3CHRM2 | |
| Phosphoric Acid SCHEMBL7192564 | 0.86 | CHRM5 (0.55) | THRBCHRM5CHRM1CHRM3CHRM2 | |
| Phosphocholine SCHEMBL1949342 | 0.85 | TSHR (0.51) | THRBSMN1; SMN2MAPTTSHRADRA1A | |
| Phosphoric Acid SCHEMBL386469 | 0.85 | CHRM5 (0.57) | THRBCHRM5CHRM1CHRM3CHRM2 | |
| Phosphocholine SCHEMBL14738989 | 0.84 | GALR3 (0.41) | THRBCHRM5CHRM1CHRM3CHRM2 | |
| Phosphocholine SCHEMBL12979922 | 0.83 | SMN1; SMN2 (0.45) | THRBCHRM5CHRM1CHRM3CHRM2 | |
| SCHEMBL24982077 | 0.82 | THRB (0.40) | THRBCHRM5CHRM1CHRM3CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6924338-B1 | Comprising an addition copolymer with one monomer having zwitterionic pendant group, ammonium phosphate inner salt , and a hydrophobic addition homopolymer; biocompatiable, forming micro-phase segregated structure, biomedical application | BIOCOMPATIBLES UK LIMITED (GB) | 2005-08-02 | — | — | US | disclosed |
| US-6186974-B1 | Device for use in the eye | UNIVERSITY COLLEGE LONDON AND MOORFIELDS EYE HOSPITAL NHS TRUST (GB) | 2001-02-13 | — | — | US | disclosed |
| EP-0977531-A1 | DEVICE FOR USE IN THE EYE | Moorfields Eye Hospital (GB) | 2000-02-09 | — | — | EP | disclosed |
| WO-1998030181-A1 | DEVICE FOR USE IN THE EYE | UNIVERSITY COLLEGE LONDON (GB) | 1998-07-16 | — | — | WO | disclosed |