Phosphocholine

Phosphocholine

SCHEMBL1949342

C=C(C)C(=O)OCCCC.C[N+](C)(C)CCOP(=O)([O-])O

nearest known ligand 0.51

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.51
LMNA P02545 1/20 0.47
ESR1 P03372 1/20 0.47
ADORA3 P0DMS8 1/20 0.47
CDC25A P30304 1/20 0.47
AGTR1 P30556 1/20 0.47
AKT1 P31749 1/20 0.47
ADRA1A P35348 1/20 0.47
KCNH2 Q12809 1/20 0.47
ADRA1D P25100 1/20 0.42
PTAFR P25105 1/20 0.42
HTR1D P28221 1/20 0.42
HTR2C P28335 1/20 0.42
ADRA1B P35368 1/20 0.42
DRD3 P35462 1/20 0.42
TMEM97 Q5BJF2 1/20 0.42
MAPT P10636 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.41
NR5A2 O00482 1/20 0.41
NR5A1 Q13285 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphocholine SCHEMBL28111186 0.89 TSHR (0.54) TSHRLMNAESR1ADORA3CDC25A
SCHEMBL368310 0.88 LMNA (0.56) TSHRLMNAESR1ADORA3CDC25A
SCHEMBL28329138 0.87 TSHR (0.51) TSHRLMNAESR1ADORA3CDC25A
Phosphocholine SCHEMBL14738989 0.86 GALR3 (0.41) TSHRLMNAESR1ADORA3CDC25A
SCHEMBL27910406 0.86 TSHR (0.50) TSHRLMNAESR1ADORA3CDC25A
Phosphocholine SCHEMBL12979922 0.85 SMN1; SMN2 (0.45) LMNAESR1ADORA3CDC25AAGTR1
SCHEMBL6462016 0.85 THRB (0.45) TSHRLMNAESR1ADORA3CDC25A
Water SCHEMBL28109847 0.85 TSHR (0.49) TSHRLMNAESR1ADORA3CDC25A
Hydrochloric Acid SCHEMBL6114873 0.84 TSHR (0.66) TSHRLMNAADRA1AMAPTSMN1; SMN2
SCHEMBL3923049 0.84 LMNA (0.64) TSHRLMNAESR1ADORA3CDC25A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8343529-B2 Implantable drug delivery devices having alternating hydrophilic and amphiphillic polymer layers ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) 2013-01-01 US claimed
US-20120225303-A1 Implantable Drug Delivery Devices Having Alternating Hydrophilic And Amphiphilic Polymer Layers ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) 2012-09-06 US claimed
US-8202529-B2 Implantable drug delivery devices having alternating hydrophilic and amphiphilic polymer layers ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) 2012-06-19 US claimed
US-20110137243-A1 Coating On A Balloon Device ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) 2011-06-09 US claimed
WO-2009148777-A2 IMPLANTABLE DRUG DELIVERY DEVICES HAVING ALTERNATING HYDROPHILIC AND AMPHIPHILIC POLYMER LAYERS ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) 2009-12-10 WO claimed
US-20090297575-A1 Implantable Drug Delivery Devices Having Alternating Hyrdrophilic And Amphiphilic Polymer Layers ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) 2009-12-03 US claimed
EP-4051778-A1 METHODS AND COMPOSITIONS FOR ASSEMBLY OF BIOLOGICAL NANOPORES Stratos Genomics Inc. (US) 2022-09-07 EP disclosed
WO-2021087118-A1 METHODS AND COMPOSITIONS FOR ASSEMBLY OF BIOLOGICAL NANOPORES STRATOS GENOMICS, INC. (US) 2021-05-06 WO disclosed
EP-3334840-A1 SINGLE MOLECULE NUCLEIC ACID SEQUENCING WITH MOLECULAR SENSOR COMPLEXES Stratos Genomics, Inc. (US) 2018-06-20 EP disclosed
US-20180044725-A1 POLYNUCLEOTIDE BINDING PROTEIN SEQUENCING Roche Sequencing Solutions, Inc. 2018-02-15 US disclosed
EP-3265589-A1 POLYNUCLEOTIDE BINDING PROTEIN SEQUENCING CROSS REFERENCE TO RELATED APPLICATIONS Stratos Genomics, Inc. (US) 2018-01-10 EP disclosed
US-20170159115-A1 SINGLE MOLECULE NUCLEIC ACID SEQUENCING WITH MOLECULAR SENSOR COMPLEXES Roche Sequencing Solutions, Inc. 2017-06-08 US disclosed
WO-2017027518-A1 SINGLE MOLECULE NUCLEIC ACID SEQUENCING WITH MOLECULAR SENSOR COMPLEXES STRATOS GENOMICS, INC. (US) 2017-02-16 WO disclosed
US-8343529-B2 Implantable drug delivery devices having alternating hydrophilic and amphiphillic polymer layers ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) 2013-01-01 US disclosed
US-20120225303-A1 Implantable Drug Delivery Devices Having Alternating Hydrophilic And Amphiphilic Polymer Layers ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) 2012-09-06 US disclosed
US-8202529-B2 Implantable drug delivery devices having alternating hydrophilic and amphiphilic polymer layers ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) 2012-06-19 US disclosed
US-20110137243-A1 Coating On A Balloon Device ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) 2011-06-09 US disclosed
US-20110129514-A1 Hygroscopic coating on a balloon device ABBOTT CARDIOVASCULAR SYSTEMS INC. 2011-06-02 US disclosed
WO-2009148777-A2 IMPLANTABLE DRUG DELIVERY DEVICES HAVING ALTERNATING HYDROPHILIC AND AMPHIPHILIC POLYMER LAYERS ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) 2009-12-10 WO disclosed
US-20090297575-A1 Implantable Drug Delivery Devices Having Alternating Hyrdrophilic And Amphiphilic Polymer Layers ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) 2009-12-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110137243-A1 Coating On A Balloon Device HSPA5, TNNI3, TNNT2 TSHR 3813/4885LMNA 781/4885ESR1 1752/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.