Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | AHR | P35869 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | HBB | P68871 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22351869 | 0.81 | ALDH1A1 (0.39) | ALDH1A1HSD17B10HIF1ACYP1B1L3MBTL1 | |
| SCHEMBL23527426 | 0.79 | ALDH1A1 (0.43) | ALDH1A1HSD17B10HIF1ACYP1B1L3MBTL1 | |
| SCHEMBL4612665 | 0.74 | ALDH1A1 (0.46) | ALDH1A1HSD17B10HIF1ACYP1B1L3MBTL1 | |
| SCHEMBL24787457 | 0.71 | ALDH1A1 (0.43) | ALDH1A1HSD17B10HIF1ACYP1B1L3MBTL1 | |
| SCHEMBL15511865 | 0.70 | ALDH1A1 (0.43) | ALDH1A1HSD17B10HIF1ACYP1B1KDM4E | |
| SCHEMBL23664 | 0.70 | ALDH1A1 (0.72) | ALDH1A1HSD17B10HIF1ACYP1B1L3MBTL1 | |
| SCHEMBL4848746 | 0.70 | ALDH1A1 (0.72) | ALDH1A1HSD17B10HIF1ACYP1B1L3MBTL1 | |
| SCHEMBL4853659 | 0.70 | ALDH1A1 (0.72) | ALDH1A1HSD17B10HIF1ACYP1B1L3MBTL1 | |
| SCHEMBL29532882 | 0.70 | ALDH1A1 (0.72) | ALDH1A1HSD17B10HIF1ACYP1B1L3MBTL1 | |
| SCHEMBL4614015 | 0.69 | ALDH1A1 (0.50) | ALDH1A1HSD17B10HIF1ACYP1B1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050143254-A1 | Haloaluminoxane compositions, their preparation, and their use in catalysis | W. R. GRACE & CO.-CONN. | 2005-06-30 | — | — | US | disclosed |