SCHEMBL6462230

SCHEMBL6462230

C=CCOC(=O)Cn1cnnn1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.49
ALOX15 P16050 1/20 0.49
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
KDM4E B2RXH2 2/20 0.47
POLB P06746 1/20 0.47
ALOX12 P18054 1/20 0.47
RECQL P46063 1/20 0.47
HBB P68871 1/20 0.47
ALDH1A1 P00352 3/20 0.44
NPSR1 Q6W5P4 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
HMOX1 P09601 1/20 0.39
TSHR P16473 1/20 0.39
ALPG P10696 1/20 0.38
TP53 P04637 2/20 0.35
GAA P10253 1/20 0.35
MAPT P10636 1/20 0.35
CYP3A4 P08684 1/20 0.34
RAB9A P51151 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10633527 0.80 HSD17B10 (0.61) HSD17B10ALOX15MEN1KMT2AKDM4E
SCHEMBL16586879 0.77 NPSR1 (0.43) NPSR1TSHRCYP3A4RAB9A
SCHEMBL22118502 0.77 HSD17B10 (0.51) HSD17B10ALOX15MEN1KMT2AKDM4E
SCHEMBL9826385 0.74 NPSR1 (0.43) MEN1KMT2AKDM4ENPSR1MAPT
SCHEMBL11786247 0.74 NPSR1 (0.47) HSD17B10ALDH1A1NPSR1TSHRCYP3A4
SCHEMBL315947 0.74 ALDH1A1 (0.52) HSD17B10ALOX15MEN1KMT2AKDM4E
SCHEMBL11456466 0.71 HMOX1 (0.59) HSD17B10ALOX15MEN1KMT2AKDM4E
SCHEMBL23069274 0.70 CYP19A1 (0.42) KMT2APOLBNPSR1L3MBTL1TSHR
SCHEMBL16586833 0.69 NPSR1 (0.47) HSD17B10MEN1KMT2AALDH1A1NPSR1
SCHEMBL16035137 0.69 HSD17B10 (0.47) HSD17B10ALOX15MEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1416054-B1 Simple enzymatic process for preparing cefazolin BIOFERMA MURCIA S A (ES) 2005-08-17 EP claimed
EP-1556500-A1 SIMPLE ENZYMATIC PROCESS FOR PREPARING CEFAZOLIN Bioferma Murcia, S.A. (ES) 2005-07-27 EP claimed
WO-2004039997-A1 SIMPLE ENZYMATIC PROCESS FOR PREPARING CEFAZOLIN BIOFERMA MURCIA, S.A. (ES) 2004-05-13 WO claimed
EP-1416054-A1 Simple enzymatic process for preparing cefazolin Bioferma Murcia, S.A. (ES) 2004-05-06 EP claimed
US-8487071-B2 Polyether polymer and production process thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-07-16 US disclosed
US-20110065889-A1 POLYETHER POLYMER AND PRODUCTION PROCESS THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-03-17 US disclosed
EP-1416054-B1 Simple enzymatic process for preparing cefazolin BIOFERMA MURCIA S A (ES) 2005-08-17 EP disclosed
EP-1556500-A1 SIMPLE ENZYMATIC PROCESS FOR PREPARING CEFAZOLIN Bioferma Murcia, S.A. (ES) 2005-07-27 EP disclosed
WO-2004039997-A1 SIMPLE ENZYMATIC PROCESS FOR PREPARING CEFAZOLIN BIOFERMA MURCIA, S.A. (ES) 2004-05-13 WO disclosed
EP-1416054-A1 Simple enzymatic process for preparing cefazolin Bioferma Murcia, S.A. (ES) 2004-05-06 EP disclosed