SCHEMBL646261

SCHEMBL646261

OC=CCNc1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.44
MAPT P10636 1/20 0.44
MAOB P27338 1/20 0.43
CA12 O43570 1/20 0.41
CA2 P00918 1/20 0.41
CA9 Q16790 1/20 0.41
CYP1A2 P05177 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
TAS2R38 P59533 2/20 0.39
TP53 P04637 1/20 0.39
EPHX1 P07099 1/20 0.39
TSHR P16473 1/20 0.39
EPHX2 P34913 1/20 0.39
CDK9 P50750 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
CLK4 Q9HAZ1 1/20 0.39
CYP3A4 P08684 1/20 0.39
HSD17B10 Q99714 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
IDO1 P14902 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL1895175 0.98 ALDH1A1 (0.43) ALDH1A1MAPTMAOBCA12CA2
SCHEMBL14647878 0.85 ALDH1A1 (0.52) ALDH1A1MAPTMAOBCA12CA2
SCHEMBL12710386 0.85 ALDH1A1 (0.52) ALDH1A1MAPTMAOBCA12CA2
SCHEMBL29072365 0.80 ALDH1A1 (0.43) ALDH1A1MAPTMAOBCA12CA2
SCHEMBL6253133 0.78 MAPT (0.43) ALDH1A1MAPTMAOBCA12CA2
SCHEMBL3952759 0.78 MAPT (0.52) ALDH1A1MAPTCA12CA2CA9
SCHEMBL2786302 0.77 ALDH1A1 (0.44) ALDH1A1MAPTMAOBCA12CA2
SCHEMBL4964230 0.77 ALDH1A1 (0.44) ALDH1A1MAPTMAOBCA12CA2
SCHEMBL7713318 0.77 ALDH1A1 (0.44) ALDH1A1MAPTMAOBCA12CA2
SCHEMBL2350761 0.77 MAPT (0.44) ALDH1A1MAPTCA12CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 182 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1986606-B1 PHENYLEPHRINE-CONTAINING LIQUID FORMULATIONS WYETH LLC (US) 2019-04-10 EP claimed
US-20150182478-A1 CHEWABLE TABLET CONTAINING PHENYLEPHRINE WYETH CORP (US) 2015-07-02 US claimed
US-20150150976-A1 PHENYLEPHRINE-CONTAINING LIQUID FORMULATIONS HALEON US HOLDINGS LLC 2015-06-04 US claimed
US-8940796-B2 Phenylephrine liquid formulations WYETH LLC (US) 2015-01-27 US claimed
EP-1414803-B1 PYRAZOLYLCARBOXANILIDES AS FUNGICIDES BAYER CROPSCIENCE AG (DE) 2012-12-12 EP claimed
EP-2351554-A1 Enhanced stability phenylephrine liquid compositions Wyeth LLC (US) 2011-08-03 EP claimed
EP-2316425-A1 Liquid formulations comprising an active agent, glycerine and sorbitol Wyeth LLC (US) 2011-05-04 EP claimed
CN-101505738-A Chewable tablet containing phenylephrine WYETH CORP (US) 2009-08-12 CN claimed
EP-2043619-A2 CHEWABLE TABLET CONTAINING PHENYLEPHRINE Wyeth (US) 2009-04-08 EP claimed
EP-2040672-A2 ENHANCED STABILITY PHENYLEPHRINE LIQUID COMPOSITIONS Wyeth (US) 2009-04-01 EP claimed
EP-1986606-A2 PHENYLEPHRINE-CONTAINING LIQUID FORMULATIONS Wyeth a Corporation of the State of Delaware (US) 2008-11-05 EP claimed
US-20080026055-A1 Chewable tablet containing phenylephrine WYETH (US) 2008-01-31 US claimed
WO-2008013710-A2 CHEWABLE TABLET CONTAINING PHENYLEPHRINE WYETH (US) 2008-01-31 WO claimed
US-20080014274-A1 Enhanced stability phenylephrine liquid compositions WYETH (US) 2008-01-17 US claimed
WO-2008008364-A2 ENHANCED STABILITY PHENYLEPHRINE LIQUID COMPOSITIONS WYETH (US) 2008-01-17 WO claimed
WO-2007098128-A2 PHENYLEPHRINE-CONTAINING LIQUID FORMULATIONS WYETH (US) 2007-08-30 WO claimed
US-20070197661-A1 Phenylephrine liquid formulations WYETH (US) 2007-08-23 US claimed
US-6955824-B1 Inhalation composition containing lactose pellets GLAXO GROUP LIMITED (GB) 2005-10-18 US claimed
US-20040204470-A1 Pyrazoylcarboxanilides as fungicides BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2004-10-14 US claimed
US-4235730-A DISPERSANTS TEXACO INC. (US) 1980-11-25 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040204470-A1 Pyrazoylcarboxanilides as fungicides CYP1A1, CYP1B1, CYP2E1 ALDH1A1 358/4885MAPT 4329/4885MAOB 1979/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.