SCHEMBL6253133

SCHEMBL6253133

Nc1ccc(NCC=CO)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.43
RAB9A P51151 3/20 0.43
APP P05067 1/20 0.41
MEN1 O00255 5/20 0.39
KMT2A Q03164 5/20 0.39
PKM P14618 2/20 0.39
LMNA P02545 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
POLB P06746 1/20 0.39
APEX1 P27695 1/20 0.39
CA12 O43570 3/20 0.38
CA1 P00915 3/20 0.38
CA2 P00918 3/20 0.38
CA9 Q16790 3/20 0.38
CYP2C19 P33261 2/20 0.37
MAOA P21397 1/20 0.37
MAOB P27338 1/20 0.37
ALDH1A1 P00352 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6275568 0.79 APP (0.44) MAPTRAB9AAPPMEN1KMT2A
SCHEMBL3952759 0.79 MAPT (0.52) MAPTRAB9AMEN1KMT2ALMNA
SCHEMBL646261 0.78 ALDH1A1 (0.44) MAPTRAB9AMEN1KMT2ACA12
Hydrochloric Acid SCHEMBL1895175 0.77 ALDH1A1 (0.43) MAPTRAB9AMEN1KMT2ACA12
SCHEMBL10987838 0.76 KDM4E (0.41) RAB9AKMT2ACA12CA1CA2
SCHEMBL11218750 0.75 GPR84 (0.41) MAPTRAB9AAPPMEN1KMT2A
SCHEMBL476573 0.74 CA12 (0.60) MAPTRAB9AAPPMEN1KMT2A
SCHEMBL6269072 0.73 MAPT (0.58) MAPTMEN1KMT2APOLBALDH1A1
SCHEMBL693125 0.73 MAOB (0.53) MAPTRAB9AAPPMEN1KMT2A
SCHEMBL11777572 0.71 APP (0.41) MAPTRAB9AAPPMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0202616-B1 METHOD FOR COLOR-DEVELOPING A SILVER HALIDE PHOTOGRAPHIC LIGHT-SENSITIVE MATERIAL KONICA CORPORATION (JP) 1991-12-11 EP claimed
US-4738917-A HIGH SPEED KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1988-04-19 US claimed
EP-1518546-A1 Dye composition comprising a secondary, hydroxyalkylated p-phenylenediamine, a coupler and an amminum salt of an inorganic acid L'OREAL (FR) 2005-03-30 EP disclosed
EP-1518540-A1 Dye composition comprising a hydroxyalkylated secondary p-phenylene diamine base, a first coupler in form of a m-diphenol and a second coupler in form of a m-aminophenol and/or a heterocycle L'OREAL (FR) 2005-03-30 EP disclosed
EP-1518547-A1 Dye composition comprising a hydroxyalkylated secondary paraphenylene diamine developer, at least one coupling agent and octyldodecanol L'OREAL (FR) 2005-03-30 EP disclosed
EP-1518539-A1 Dye composition comprising a secondary, hydroxyalkylated p-phenylendiamine, a second base and as coupling agent a m-diphenol and/or a m-aminophenol L'OREAL (FR) 2005-03-30 EP disclosed
EP-1518542-A1 Dye composition comprising at least a secondary hydroxyalkylated paraphenylenediamine base, a coupler and at least one particular cationic direct dye L'OREAL (FR) 2005-03-30 EP disclosed
EP-1518545-A1 Dye composition comprising a hydroxyalkylated secondary paraphenylene diamine developer, at least one coupling agent and an alkaline agent selected from monoethanolamine and silicates L'OREAL (FR) 2005-03-30 EP disclosed
EP-1518543-A1 Dyeing composition comprising at least a hydroxyalkylated secondary paraphenylenediamine base, at least one coupling agent and at least one sulfite or one bisulfite L'OREAL (FR) 2005-03-30 EP disclosed
EP-1518541-A1 Dye composition comprising a secondary, hydroxyalkylated p-phenylenediamine, a second base and at least two coupling compounds L'OREAL (FR) 2005-03-30 EP disclosed
EP-1518544-A1 Dye composition comprising a hydroxyalkylated secondary p-phenylene diamine base, at least one coupling agent and etidronic acid L'OREAL (FR) 2005-03-30 EP disclosed
EP-0202616-A2 Method for color-developing a silver halide photographic light-sensitive material KONICA CORPORATION (JP) 1986-11-26 EP disclosed