Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.32 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.32 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6462638 | 1.00 | MAOA (0.38) | MAOAMAOBSCN9ACRBNRAB9A | |
| SCHEMBL6455003 | 1.00 | MAOA (0.38) | MAOAMAOBSCN9ACRBNRAB9A | |
| SCHEMBL6455006 | 1.00 | MAOA (0.38) | MAOAMAOBSCN9ACRBNRAB9A | |
| SCHEMBL6452959 | 0.99 | MAOA (0.37) | MAOAMAOBSCN9ACRBNRAB9A | |
| SCHEMBL6452963 | 0.99 | MAOA (0.37) | MAOAMAOBSCN9ACRBNRAB9A | |
| SCHEMBL6456962 | 0.96 | MAOA (0.35) | MAOAMAOBSCN9ACRBNRAB9A | |
| SCHEMBL6456967 | 0.96 | MAOA (0.35) | MAOAMAOBSCN9ACRBNRAB9A | |
| SCHEMBL6459848 | 0.93 | ALDH1A1 (0.37) | MAOAMAOBSCN9ACRBNSLC6A3 | |
| SCHEMBL6459854 | 0.93 | ALDH1A1 (0.37) | MAOAMAOBSCN9ACRBNSLC6A3 | |
| SCHEMBL6452677 | 0.89 | SCN9A (0.37) | SCN9ASLC6A3SLC6A4ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |