Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CASP2 | P42575 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5423998 | 0.94 | TSHR (0.53) | TSHRRECQLMEN1KMT2AHPGD | |
| SCHEMBL6500143 | 0.86 | TSHR (0.42) | TSHRRECQLMEN1KMT2AHPGD | |
| SCHEMBL11505724 | 0.86 | RECQL (0.58) | TSHRRECQLMEN1KMT2AHPGD | |
| SCHEMBL4849009 | 0.79 | FAAH (0.61) | TSHRRECQLMEN1KMT2AEPHX2 | |
| SCHEMBL500235 | 0.78 | TDP1 (0.57) | TSHRRECQLMEN1KMT2AGAA | |
| SCHEMBL8639742 | 0.77 | TSHR (0.46) | TSHRRECQLMEN1KMT2AHPGD | |
| SCHEMBL13241886 | 0.77 | FAAH (0.64) | RECQLMEN1KMT2AEPHX2CASP2 | |
| SCHEMBL14071552 | 0.77 | FAAH (0.64) | RECQLMEN1KMT2AEPHX2CASP2 | |
| SCHEMBL13241883 | 0.77 | FAAH (0.64) | RECQLMEN1KMT2AEPHX2CASP2 | |
| SCHEMBL2126624 | 0.77 | FAAH (0.64) | RECQLMEN1KMT2AEPHX2CASP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1286673-B8 | LIGANDS OF INTEGRIN RECEPTORS | ABBOTT GMBH & CO KG (DE) | 2005-07-20 | — | — | EP | disclosed |
| EP-1286673-A2 | LIGANDS OF INTEGRIN RECEPTORS | Basf Aktiengesellschaft (DE) | 2003-03-05 | — | — | EP | disclosed |
| WO-2002051810-A2 | INTEGRIN RECEPTOR LIGANDS | ABBOTT GMBH & CO. KG (DE) | 2002-07-04 | — | — | WO | disclosed |
| WO-2001093840-A2 | LIGANDS OF INTEGRIN RECEPTORS | BASF AG (DE) | 2001-12-13 | — | — | WO | disclosed |