SCHEMBL8639742

SCHEMBL8639742

COCNC(=O)CCC(=O)NCOC

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.46
RECQL P46063 1/20 0.44
KDM4E B2RXH2 2/20 0.35
CTSD P07339 1/20 0.35
KDM5C P41229 1/20 0.35
PHF8 Q9UPP1 1/20 0.35
KDM2A Q9Y2K7 1/20 0.35
ALDH1A1 P00352 2/20 0.34
FAAH O00519 1/20 0.34
GAA P10253 1/20 0.34
LMNA P02545 2/20 0.34
CASP2 P42575 1/20 0.33
MEN1 O00255 1/20 0.33
HPGD P15428 1/20 0.33
KMT2A Q03164 1/20 0.33
CNR1 P21554 1/20 0.33
POLB P06746 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6222618 0.91 ALDH1A1 (0.46) TSHRRECQLKDM4EALDH1A1FAAH
SCHEMBL11505724 0.90 RECQL (0.58) TSHRRECQLALDH1A1FAAHGAA
SCHEMBL17049333 0.87
SCHEMBL8644277 0.86 TSHR (0.38) TSHRRECQLCTSDALDH1A1GAA
SCHEMBL24070642 0.84 TSHR (0.64) TSHRRECQLKDM4EALDH1A1FAAH
SCHEMBL22746115 0.84 FAAH (0.52) TSHRRECQLALDH1A1FAAHCASP2
SCHEMBL15671630 0.84 TSHR (0.39) TSHRRECQLKDM4ELMNAHPGD
SCHEMBL6500143 0.82 TSHR (0.42) TSHRRECQLKDM4EALDH1A1GAA
SCHEMBL4849009 0.82 FAAH (0.61) TSHRRECQLFAAHCASP2MEN1
SCHEMBL1965413 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0458325-B1 Negative photosensitive composition and method for forming a resist pattern MITSUBISHI CHEM CORP (JP) 1998-08-19 EP disclosed
EP-0458325-A1 Negative photosensitive composition and method for forming a resist pattern Mitsubishi Chemical Corporation (JP) 1991-11-27 EP disclosed