Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | GRM3 | Q14832 | 4/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6462632 | 1.00 | SLC6A2 (0.40) | SLC6A2SLC6A4SLC6A3DRD2APP | |
| SCHEMBL6463486 | 0.92 | DRD2 (0.46) | SLC6A2SLC6A4SLC6A3DRD2RAB9A | |
| SCHEMBL6463482 | 0.92 | DRD2 (0.46) | SLC6A2SLC6A4SLC6A3DRD2RAB9A | |
| SCHEMBL6459752 | 0.90 | DRD2 (0.41) | SLC6A2SLC6A4SLC6A3DRD2APP | |
| SCHEMBL6459755 | 0.90 | DRD2 (0.41) | SLC6A2SLC6A4SLC6A3DRD2APP | |
| SCHEMBL6459069 | 0.88 | DRD2 (0.43) | SLC6A2SLC6A4SLC6A3DRD2RAB9A | |
| SCHEMBL6459075 | 0.88 | DRD2 (0.43) | SLC6A2SLC6A4SLC6A3DRD2RAB9A | |
| SCHEMBL6452339 | 0.88 | RAB9A (0.40) | SLC6A2SLC6A4SLC6A3DRD2APP | |
| SCHEMBL6452336 | 0.88 | RAB9A (0.40) | SLC6A2SLC6A4SLC6A3DRD2APP | |
| SCHEMBL6464016 | 0.87 | RAB9A (0.39) | SLC6A2SLC6A4SLC6A3DRD2APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |