Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6465891 | 0.85 | PDCD1 (0.34) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL29874524 | 0.85 | BRD4 (0.32) | BRD4CREBBPKIF11PARP1 | |
| Hydrochloric Acid SCHEMBL6465119 | 0.85 | BRD4 (0.32) | BRD4CREBBPKIF11PARP1 | |
| Hydrochloric Acid SCHEMBL6465000 | 0.84 | KIF11 (0.31) | KIF11PARP1 | |
| Hydrochloric Acid SCHEMBL1022319 | 0.83 | — | — | |
| Hydrochloric Acid SCHEMBL29949206 | 0.82 | BRD4 (0.33) | BRD4CREBBPKIF11PARP1 | |
| Hydrochloric Acid SCHEMBL2234634 | 0.82 | BRD4 (0.31) | BRD4CREBBPKIF11PARP1 | |
| Hydrochloric Acid SCHEMBL5351713 | 0.82 | BRD4 (0.31) | BRD4CREBBPKIF11PARP1 | |
| Hydrochloric Acid SCHEMBL30203909 | 0.82 | BRD4 (0.31) | BRD4CREBBPKIF11PARP1 | |
| Hydrochloric Acid SCHEMBL6466714 | 0.82 | KIF11 (0.30) | KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6900343-B1 | Method for the purification of metallocenes | BASELL POLYOLEFINE GMBH (DE) | 2005-05-31 | — | — | US | disclosed |