SCHEMBL6462889

SCHEMBL6462889

Cc1ccc(S(=O)(=O)NC(=O)Nc2ccc(OCCOc3ccc(NC(=O)NS(=O)(=O)c4ccc(C)cc4)cc3)cc2)cc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 9/20 0.73
CA12 O43570 2/20 0.67
CA1 P00915 2/20 0.67
CA2 P00918 2/20 0.67
CA4 P22748 2/20 0.67
CA6 P23280 2/20 0.67
CA5A P35218 2/20 0.67
CA7 P43166 2/20 0.67
CA9 Q16790 2/20 0.67
CA13 Q8N1Q1 2/20 0.67
CA14 Q9ULX7 2/20 0.67
TP53 P04637 1/20 0.67
LMNA P02545 1/20 0.66
PPARG P37231 1/20 0.64
RAB9A P51151 1/20 0.64
RXFP1 Q9HBX9 1/20 0.64
NR2E3 Q9Y5X4 1/20 0.64
NCOR2 Q9Y618 1/20 0.64
MEN1 O00255 2/20 0.60
KMT2A Q03164 2/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26267 0.94 HRH3 (0.72) HRH3CA12CA1CA2CA4
SCHEMBL8383136 0.91 HRH3 (0.65) HRH3CA12CA1CA2CA4
SCHEMBL6470643 0.89 SMN1; SMN2 (0.62) HRH3CA12CA1CA2CA9
SCHEMBL8662949 0.89 HRH3 (0.72) HRH3CA12CA1CA2CA9
SCHEMBL5517478 0.87 CA12 (0.72) HRH3CA12CA1CA2CA4
SCHEMBL6243996 0.87 CA12 (0.85) CA12CA1CA2CA4CA6
SCHEMBL1928662 0.87 CA12 (0.85) CA12CA1CA2CA4CA6
SCHEMBL5187356 0.86 CA12 (0.70) HRH3CA12CA1CA2CA4
SCHEMBL5184799 0.85 AR (0.70) HRH3CA12CA1CA2CA4
SCHEMBL5198399 0.84 CA12 (0.67) HRH3CA12CA1CA2CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0610653-B1 Thermosensitive recording material NEW OJI PAPER CO LTD (JP) 1997-04-16 EP claimed
EP-0620122-B1 Thermosensitive recording material NEW OJI PAPER CO LTD (JP) 1996-03-13 EP claimed
US-5446010-A Substrate sheet, thermosensitive colored image forming layer containing colorless dye precursor, binder, color developing agent having sulfonylureido group, aromatic amide sensitizer; storage stability NEW OJI PAPER CO., LTD. (JP) 1995-08-29 US claimed
US-5444036-A Arylsulfonylureido compound, acetoacetanilide compound, sulfonamide derivative; storage stability NEW OIL PAPER CO., LTD. (JP) 1995-08-22 US claimed
EP-0535887-B1 Thermosensitive recording material NEW OJI PAPER CO LTD (JP) 1995-07-19 EP claimed
EP-0542556-B1 Thermosensitive recording material NEW OJI PAPER CO LTD (JP) 1995-07-19 EP claimed
EP-0620122-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1994-10-19 EP claimed
EP-0610653-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1994-08-17 EP claimed
US-5314859-A Thermosensitive recording material OJI PAPER CO., LTD. (JP) 1994-05-24 US claimed
US-5256618-A Using a sulfonylurea or -thiourea-type developer and leuco dye. resistance to oil and fats, e.g, plasticizer, moisture and heat; colorfastness; storage stability; thermography OJI PAPER CO., LTD. (JP) 1993-10-26 US claimed
EP-0542556-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1993-05-19 EP claimed
EP-0535887-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1993-04-07 EP claimed
US-20050255998-A1 Mixture of colour developers CIBA SPECIALTY CHEMICALS CORP. 2005-11-17 US disclosed
US-20050106491-A1 Heat sensitive recording material CIBA SPECIALTY CHEMICALS CORP. 2005-05-19 US disclosed
EP-1040933-B1 Double-side recording medium OJI PAPER CO (JP) 2004-03-03 EP disclosed
EP-0832757-B1 REVERSIBLE THERMAL RECORDING MEDIUM OJI PAPER CO (JP) 2001-08-22 EP disclosed
US-5314859-A Thermosensitive recording material OJI PAPER CO., LTD. (JP) 1994-05-24 US disclosed
US-5256618-A Using a sulfonylurea or -thiourea-type developer and leuco dye. resistance to oil and fats, e.g, plasticizer, moisture and heat; colorfastness; storage stability; thermography OJI PAPER CO., LTD. (JP) 1993-10-26 US disclosed
EP-0542556-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1993-05-19 EP disclosed
EP-0535887-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1993-04-07 EP disclosed