SCHEMBL8383136

SCHEMBL8383136

CCOc1ccc(NC(=O)NS(=O)(=O)c2ccc(C)cc2)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 2/20 0.65
CA12 O43570 2/20 0.65
CA1 P00915 2/20 0.65
CA2 P00918 2/20 0.65
CA4 P22748 2/20 0.65
CA6 P23280 2/20 0.65
CA5A P35218 2/20 0.65
CA7 P43166 2/20 0.65
CA9 Q16790 2/20 0.65
CA13 Q8N1Q1 2/20 0.65
CA14 Q9ULX7 2/20 0.65
TP53 P04637 1/20 0.65
LMNA P02545 3/20 0.64
PPARG P37231 1/20 0.62
RAB9A P51151 1/20 0.62
RXFP1 Q9HBX9 1/20 0.62
NR2E3 Q9Y5X4 1/20 0.62
NCOR2 Q9Y618 1/20 0.62
MEN1 O00255 2/20 0.59
KMT2A Q03164 2/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6470643 0.91 SMN1; SMN2 (0.62) HRH3CA12CA1CA2CA9
SCHEMBL6462889 0.91 HRH3 (0.73) HRH3CA12CA1CA2CA4
SCHEMBL26267 0.90 HRH3 (0.72) HRH3CA12CA1CA2CA4
SCHEMBL9485899 0.88 CYP3A4 (0.55) HRH3CA12CA1CA2CA9
SCHEMBL5517478 0.86 CA12 (0.72) HRH3CA12CA1CA2CA4
SCHEMBL6881573 0.86 MAPT (0.58) HRH3LMNAMEN1KMT2AMAPT
SCHEMBL6243996 0.86 CA12 (0.85) CA12CA1CA2CA4CA6
SCHEMBL1928662 0.86 CA12 (0.85) CA12CA1CA2CA4CA6
SCHEMBL5187356 0.85 CA12 (0.70) HRH3CA12CA1CA2CA4
SCHEMBL6325438 0.84 CA12 (0.65) HRH3CA12CA1CA2CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5928988-A CONTAINING SULFONYLUREA COLOR DEVELOPER OJI PAPER CO., LTD. (JP) 1999-07-27 US disclosed
EP-0615859-B1 Thermosensitive recording material OJI PAPER CO (JP) 1998-06-03 EP disclosed
US-5702850-A COMPRISES A COLOR-DEVELOPING AROMATIC COMPOUND REACTIVE WITH A COLORLESS DYE PRECURSOR OF RECORDING MATERIAL TO DEVELOP COLOR ON HEATING AND TO MAKE COLOR DISAPPEAR UPON HEATING AT LOWER TERMPERATURE THAN PREVIOUS COLOR DEVELOPING TEMPERATURE NEW OJI PAPER CO., LTD. (JP) 1997-12-30 US disclosed
US-5449657-A Sulfonyl (thio)ureas NEW OJI PAPER CO., LTD. (JP) 1995-09-12 US disclosed
EP-0615859-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1994-09-21 EP disclosed