Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | HRH3 | Q9Y5N1 | 12/20 | 0.60 |
| ▸ | CA12 | O43570 | 1/20 | 0.59 |
| ▸ | CA1 | P00915 | 1/20 | 0.59 |
| ▸ | CA2 | P00918 | 1/20 | 0.59 |
| ▸ | CA9 | Q16790 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8383136 | 0.91 | HRH3 (0.65) | SMN1; SMN2HRH3CA12CA1CA2 | |
| SCHEMBL9485899 | 0.90 | CYP3A4 (0.55) | SMN1; SMN2HRH3CA12CA1CA2 | |
| SCHEMBL6462889 | 0.89 | HRH3 (0.73) | HRH3CA12CA1CA2CA9 | |
| SCHEMBL8662949 | 0.89 | HRH3 (0.72) | SMN1; SMN2HRH3CA12CA1CA2 | |
| SCHEMBL6881573 | 0.87 | MAPT (0.58) | SMN1; SMN2HRH3MAPTLMNAKMT2A | |
| SCHEMBL26267 | 0.86 | HRH3 (0.72) | SMN1; SMN2HRH3CA12CA1CA2 | |
| SCHEMBL9483024 | 0.84 | MAPT (0.55) | SMN1; SMN2HRH3MAPTLMNAKMT2A | |
| SCHEMBL7776051 | 0.80 | NPC1 (0.57) | SMN1; SMN2MAPTLMNAKMT2AMEN1 | |
| SCHEMBL7770070 | 0.80 | NPC1 (0.57) | SMN1; SMN2MAPTLMNAKMT2AMEN1 | |
| SCHEMBL4113545 | 0.80 | MAPT (0.68) | SMN1; SMN2CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050255998-A1 | Mixture of colour developers | CIBA SPECIALTY CHEMICALS CORP. | 2005-11-17 | — | — | US | disclosed |