Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALPL | P05186 | 2/20 | 0.38 |
| ▸ | ALPG | P10696 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | XDH | P47989 | 1/20 | 0.34 |
| ▸ | MARS1 | P56192 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1481883 | 0.84 | SMN1; SMN2 (0.49) | SMN1; SMN2MEN1MAPTKMT2ANPC1 | |
| SCHEMBL1481885 | 0.84 | SMN1; SMN2 (0.49) | SMN1; SMN2MEN1MAPTKMT2ANPC1 | |
| SCHEMBL1482814 | 0.83 | MEN1 (0.46) | SMN1; SMN2MEN1MAPTKMT2ANPC1 | |
| SCHEMBL1482813 | 0.83 | MEN1 (0.46) | SMN1; SMN2MEN1MAPTKMT2ANPC1 | |
| SCHEMBL1481927 | 0.82 | MEN1 (0.45) | SMN1; SMN2MEN1MAPTKMT2ANPC1 | |
| SCHEMBL1481925 | 0.82 | MEN1 (0.45) | SMN1; SMN2MEN1MAPTKMT2ANPC1 | |
| SCHEMBL1480314 | 0.81 | RAB9A (0.41) | SMN1; SMN2MEN1MAPTKMT2ANPC1 | |
| SCHEMBL1480315 | 0.81 | RAB9A (0.41) | SMN1; SMN2MEN1MAPTKMT2ANPC1 | |
| SCHEMBL1481356 | 0.81 | NPC1 (0.35) | SMN1; SMN2MEN1MAPTKMT2ANPC1 | |
| SCHEMBL1480766 | 0.78 | PTGES (0.44) | SMN1; SMN2MEN1MAPTKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1594847-A2 | SUBSTITUTED AZOLE DERIVATIVES AS THERAPEUTIC AGENTS | Transtech Pharma, Inc. (US) | 2005-11-16 | — | — | EP | disclosed |
| WO-2004071447-A9 | SUBSTITUTED AZOLE DERIVATIVES AS THERAPEUTIC AGENTS | TRANSTECH PHARMA INC (US) | 2005-10-13 | — | — | WO | disclosed |
| WO-2004071447-A2 | SUBSTITUTED AZOLE DERIVATIVES AS THERAPEUTIC AGENTS | TRANSTECH PHARMA INC. (US) | 2004-08-26 | — | — | WO | disclosed |