Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | PTGDR2 | Q9Y5Y4 | 7/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6246905 | 0.99 | CCR1 (0.51) | CCR1SMN1; SMN2LMNAGAAHTT | |
| SCHEMBL6466922 | 0.98 | CCR1 (0.50) | CCR1SMN1; SMN2LMNAGAAHTT | |
| SCHEMBL6245957 | 0.92 | SMN1; SMN2 (0.48) | CCR1SMN1; SMN2LMNAGAAHTT | |
| SCHEMBL6248257 | 0.90 | SMN1; SMN2 (0.48) | CCR1SMN1; SMN2LMNAGAAHTT | |
| SCHEMBL6244886 | 0.90 | SMN1; SMN2 (0.52) | CCR1SMN1; SMN2LMNAGAAHTT | |
| SCHEMBL6245599 | 0.90 | KDM4E (0.47) | CCR1SMN1; SMN2LMNAGAAHTT | |
| SCHEMBL6464938 | 0.89 | LMNA (0.54) | CCR1SMN1; SMN2LMNAGAAHTT | |
| SCHEMBL6248164 | 0.89 | SMN1; SMN2 (0.47) | CCR1SMN1; SMN2LMNAGAAHTT | |
| SCHEMBL6247746 | 0.89 | ALDH1A1 (0.48) | CCR1SMN1; SMN2LMNAMAPK1HPGD | |
| SCHEMBL6243880 | 0.88 | LMNA (0.53) | CCR1SMN1; SMN2LMNAGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050119275-A1 | Salt and crystal forms of (5-chloro-2-{2-[4-(4-fluoro-benzyl)-(2R,5S)-2,5-dimethyl-piperazin-1-yl]-2-oxo-ethoxy}-phenyl)-methanesulfonic acid | PFIZER INC. | 2005-06-02 | — | — | US | disclosed |
| WO-2004113311-A1 | AMORPHOUS UND CRYSTAL FORMS OF (5-CHLORO-2-{2- | PFIZER PRODUCTS INC. (US) | 2004-12-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050119275-A1 | Salt and crystal forms of (5-chloro-2-{2-[4-(4-fluoro-benzyl)-(2R,5S)-2,5-dimethyl-piperazin-1-yl]-2-oxo-ethoxy}-phenyl)-methanesulfonic acid | CCR1, CCR6, CCR3 | CCR1 1/4885SMN1; SMN2 1948/4885LMNA 4222/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.