Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6927140 | 0.98 | ADRA2A (0.44) | ADRA2ACYP3A4MAPK1KMT2AMEN1 | |
| SCHEMBL6017700 | 0.81 | CAPN1 (0.40) | ADRA2ACYP3A4MAPK1KMT2AMEN1 | |
| SCHEMBL1395814 | 0.80 | AKR1B1 (0.65) | ADRA2ACYP3A4MAPK1KMT2AMEN1 | |
| SCHEMBL55504 | 0.80 | AKR1B1 (0.65) | ADRA2ACYP3A4MAPK1KMT2AMEN1 | |
| SCHEMBL11832033 | 0.80 | AKR1B1 (0.43) | ADRA2ACYP3A4MAPK1KMT2AMEN1 | |
| SCHEMBL1701239 | 0.80 | AKR1B1 (0.65) | ADRA2ACYP3A4MAPK1KMT2AMEN1 | |
| SCHEMBL29397431 | 0.80 | AKR1B1 (0.65) | ADRA2ACYP3A4MAPK1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL5297667 | 0.78 | ADRA2A (0.65) | ADRA2ACYP3A4MAPK1KMT2AMEN1 | |
| Ammonia Solution, Strong SCHEMBL25360718 | 0.78 | AKR1B1 (0.63) | ADRA2ACYP3A4MAPK1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL29008321 | 0.78 | AKR1B1 (0.63) | ADRA2ACYP2C9HSD17B10AKR1B1GMNN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050197350-A1 | Novel quinoline, tetrahydroquinazoline, and pyrimidine derivatives and methods of treatment related to the use thereof | TAISHO PHARMACEUTICAL CO., LTD. | 2005-09-08 | — | — | US | disclosed |
| US-4627874-A | RICE PRODUCTION | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1986-12-09 | — | — | US | disclosed |
| US-4502883-A | CONTAINING CHLORINE | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1985-03-05 | — | — | US | disclosed |
| US-4455164-A | HALOGENATED DERIVATIVES | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1984-06-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050197350-A1 | Novel quinoline, tetrahydroquinazoline, and pyrimidine derivatives and methods of treatment related to the use thereof | HCRTR2, MCHR1, MCHR2 | ADRA2A 117/4885CYP3A4 284/4885MAPK1 2507/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.