Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC3 | Q13507 | 1/20 | 0.36 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 6/20 | 0.35 |
| ▸ | TRPV4 | Q9HBA0 | 4/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
| ▸ | FASN | P49327 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.31 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.31 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.31 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6463445 | 1.00 | TRPC3 (0.36) | TRPC3TRPC6KDM1ATRPV4GPR119 | |
| SCHEMBL12152977 | 0.90 | KDM1A (0.38) | TRPC3TRPC6KDM1ATRPV4GPR119 | |
| SCHEMBL12892553 | 0.90 | KDM1A (0.38) | TRPC3TRPC6KDM1ATRPV4GPR119 | |
| SCHEMBL6452790 | 0.89 | TRPA1 (0.33) | KDM1ATRPV4GPR119TRPA1S1PR1 | |
| SCHEMBL6452794 | 0.89 | TRPA1 (0.33) | KDM1ATRPV4GPR119TRPA1S1PR1 | |
| SCHEMBL6454642 | 0.88 | TRPV4 (0.33) | TRPC3TRPC6KDM1ATRPV4GPR119 | |
| SCHEMBL6454645 | 0.88 | TRPV4 (0.33) | TRPC3TRPC6KDM1ATRPV4GPR119 | |
| SCHEMBL6456829 | 0.88 | FASN (0.33) | KDM1AFASNALDH1A1KMT2A | |
| SCHEMBL6456828 | 0.88 | FASN (0.33) | KDM1AFASNALDH1A1KMT2A | |
| SCHEMBL6452687 | 0.88 | TRPV4 (0.35) | TRPC3TRPC6KDM1ATRPV4GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |