Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 10/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1253295 | 0.84 | TAAR1 (0.50) | TAAR1HTR2AHTR2CHTR2BMAPT | |
| SCHEMBL1251942 | 0.84 | TAAR1 (0.55) | TAAR1HTR2AHTR2CHTR2BMAPT | |
| SCHEMBL1252286 | 0.82 | TAAR1 (0.55) | TAAR1HTR2AHTR2CHTR2BL3MBTL1 | |
| Nitrogen SCHEMBL10975955 | 0.82 | MAPT (0.47) | MAPTNPSR1L3MBTL1GABRA1GABRB2 | |
| SCHEMBL11145730 | 0.81 | MAPT (0.41) | MAPTNPSR1L3MBTL1GABRA1GABRB2 | |
| SCHEMBL1253352 | 0.81 | TAAR1 (0.40) | TAAR1HTR2AHTR2CHTR2BGABRA1 | |
| SCHEMBL1254108 | 0.81 | TAAR1 (0.61) | TAAR1HTR2AHTR2CHTR2B | |
| SCHEMBL1252234 | 0.77 | TAAR1 (0.56) | TAAR1HTR2AHTR2CHTR2BMAPT | |
| SCHEMBL23251431 | 0.77 | L3MBTL1 (0.43) | MAPTNPSR1L3MBTL1GABRA1GABRB2 | |
| SCHEMBL12482259 | 0.77 | GABRA1 (0.45) | MAPTNPSR1L3MBTL1GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1608377-A2 | PHARMACEUTICAL COMPOSITIONS COMPRISING INHIBITORS OF FAB I AND FURTHER ANTIBIOTICS | Affinium Pharmaceuticals, Inc. (CA) | 2005-12-28 | — | — | EP | disclosed |
| WO-2004082586-A2 | PHAMACEUTICAL COMPOSITIONS COMPRISING INHIBITORS OF FAB I AND FURTHER ANTIBIOTICS | AFFINIUM PHARMACEUTICALS, INC. (US) | 2004-09-30 | — | — | WO | disclosed |