SCHEMBL6463768

SCHEMBL6463768

CCCC(C)OC(=O)N(Br)Br

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 5/20 0.39
CNR1 P21554 1/20 0.38
CNR2 P34972 1/20 0.38
CHRM1 P11229 1/20 0.33
AKR1A1 P14550 1/20 0.33
CHRM3 P20309 1/20 0.33
HTR2A P28223 1/20 0.33
HTR2C P28335 1/20 0.33
ADRA1A P35348 1/20 0.33
HRH1 P35367 1/20 0.33
DRD3 P35462 1/20 0.33
SLC6A3 Q01959 1/20 0.33
HDAC1 Q13547 1/20 0.33
HDAC2 Q92769 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
TSHR P16473 3/20 0.32
CYP3A4 P08684 2/20 0.32
NFKB1 P19838 2/20 0.32
NPSR1 Q6W5P4 2/20 0.32
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10837232 0.88 FAAH (0.47) FAAHCNR1CNR2ALDH1A1LMNA
SCHEMBL10839825 0.86 FAAH (0.54) FAAHCNR1CNR2ALDH1A1LMNA
SCHEMBL10836646 0.85 FAAH (0.57) FAAHCNR1CNR2ALDH1A1LMNA
SCHEMBL6461670 0.83 MAPT (0.33) FAAHCHRM1TSHR
SCHEMBL6466677 0.79 FAAH (0.39) FAAHCNR1CNR2CHRM1AKR1A1
SCHEMBL30889132 0.76
SCHEMBL33485 0.75 FAAH (0.40) FAAHCNR1CNR2CHRM1AKR1A1
SCHEMBL14396410 0.73
SCHEMBL6718545 0.73
SCHEMBL13034085 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4657285-A Tubular rubber products BRIDGESTONE CORPORATION (JP) 1987-04-14 US claimed
US-10752566-B2 Solvent compositions for use as replacements for slow evaporating solvents TBF ENVIRONMENTAL TECHNOLOGY INC. (CA) 2020-08-25 US disclosed
US-20180362422-A1 SOLVENT COMPOSITIONS FOR USE AS REPLACEMENTS FOR SLOW EVAPORATING SOLVENTS AXEL PLASTICS RESEARCH LABORATORIES, INC. 2018-12-20 US disclosed
US-20180179129-A1 SOLVENT COMPOSITIONS FOR USE AS HEXANE REPLACEMENTS TBF ENVIRONMENTAL TECHNOLOGY INC. (CA) 2018-06-28 US disclosed
US-20180179476-A1 SOLVENT COMPOSITIONS FOR USE AS HEPTANE REPLACEMENTS TBF ENVIRONMENTAL TECHNOLOGY INC. (CA) 2018-06-28 US disclosed
EP-3302773-A1 SOLVENT COMPOSITIONS FOR USE AS HEPTANE REPLACEMENTS TBF Environmental Technology Inc. (CA) 2018-04-11 EP disclosed
WO-2016193866-A1 SOLVENT COMPOSITIONS FOR USE AS HEPTANE REPLACEMENTS TBF ENVIRONMENTAL TECHNOLOGY INC. (CA) 2016-12-08 WO disclosed
WO-2016193867-A1 SOLVENT COMPOSITIONS FOR USE AS HEXANE REPLACEMENTS TBF ENVIRONMENTAL TECHNOLOGY INC. (CA) 2016-12-08 WO disclosed
EP-1590397-A2 SURFACE PREPARATION OF RUBBER FOR COATINGS OR BONDING Lord Corporation (US) 2005-11-02 EP disclosed
US-6918987-B2 Surface preparation of rubber for coatings or bonding LORD CORPORATION (US) 2005-07-19 US disclosed
WO-2004072156-A2 SURFACE PREPARATION OF RUBBER FOR COATINGS OR BONDING LORD CORPORATION (US) 2004-08-26 WO disclosed
US-20040157983-A1 Surface preparation of rubber for coatings or bonding LORD CORPORATION 2004-08-12 US disclosed
US-4762589-A Method of making a tubular rubber product having a polyamide or polyester resin layer BRIDGESTONE CORPORATION (JP) 1988-08-09 US disclosed
US-4657285-A Tubular rubber products BRIDGESTONE CORPORATION (JP) 1987-04-14 US disclosed
US-4591618-A HIGH STRENGTH BONDING AGENTS BRIDGESTONE TIRE CO., LTD. (JP) 1986-05-27 US disclosed
US-4535003-A WITH HALOGEN RELEASING HALOGENOID, WAX AND FILLER BRIDGESTONE TIRE CO., LTD. (JP) 1985-08-13 US disclosed
US-4500685-A MIXTURES OF HALOSULFONAMIDE AND WAX BRIDGESTONE TIRE COMPANY LIMITED (JP) 1985-02-19 US disclosed
US-4300970-A Method of bonding vulcanized rubber to resin BRIDGESTONE TIRE COMPANY LIMITED (JP) 1981-11-17 US disclosed
US-4117036-A ANAEROBIC CURABILITY, SEALANTS BRIDGESTONE TIRE COMPANY LIMITED (JP) 1978-09-26 US disclosed