SCHEMBL6461670

SCHEMBL6461670

CCC(C)OC(=O)N(Br)Br

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.31
TSHR P16473 1/20 0.30
CHRM2 P08172 1/20 0.30
CHRM4 P08173 1/20 0.30
CHRM1 P11229 1/20 0.30
TBXA2R P21731 1/20 0.30
FAAH O00519 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6463768 0.83 FAAH (0.39) TSHRCHRM1FAAH
SCHEMBL10837232 0.79 FAAH (0.47) FAAH
SCHEMBL8455989 0.79 CHRNB2 (0.41) MAPTTSHRCHRM2CHRM4CHRM1
SCHEMBL14759451 0.79 CHRNB2 (0.41) MAPTTSHRCHRM2CHRM4CHRM1
SCHEMBL10839825 0.78 FAAH (0.54) MAPTL3MBTL1FAAH
SCHEMBL3822564 0.77 MAPT (0.33) MAPTTSHRCHRM2CHRM4CHRM1
SCHEMBL9728294 0.77 KMT2A (0.42) MAPTL3MBTL1
SCHEMBL10369020 0.77 MAPT (0.33) MAPTTSHRCHRM2CHRM4CHRM1
SCHEMBL10836646 0.77 FAAH (0.57) MAPTL3MBTL1FAAH
SCHEMBL1863804 0.76 TSHR (0.33) MAPTTSHRCHRM2CHRM4CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4657285-A Tubular rubber products BRIDGESTONE CORPORATION (JP) 1987-04-14 US claimed
US-10752566-B2 Solvent compositions for use as replacements for slow evaporating solvents TBF ENVIRONMENTAL TECHNOLOGY INC. (CA) 2020-08-25 US disclosed
US-20180362422-A1 SOLVENT COMPOSITIONS FOR USE AS REPLACEMENTS FOR SLOW EVAPORATING SOLVENTS AXEL PLASTICS RESEARCH LABORATORIES, INC. 2018-12-20 US disclosed
US-20180179129-A1 SOLVENT COMPOSITIONS FOR USE AS HEXANE REPLACEMENTS TBF ENVIRONMENTAL TECHNOLOGY INC. (CA) 2018-06-28 US disclosed
US-20180179476-A1 SOLVENT COMPOSITIONS FOR USE AS HEPTANE REPLACEMENTS TBF ENVIRONMENTAL TECHNOLOGY INC. (CA) 2018-06-28 US disclosed
WO-2016193867-A1 SOLVENT COMPOSITIONS FOR USE AS HEXANE REPLACEMENTS TBF ENVIRONMENTAL TECHNOLOGY INC. (CA) 2016-12-08 WO disclosed
EP-1590397-A2 SURFACE PREPARATION OF RUBBER FOR COATINGS OR BONDING Lord Corporation (US) 2005-11-02 EP disclosed
US-6918987-B2 Surface preparation of rubber for coatings or bonding LORD CORPORATION (US) 2005-07-19 US disclosed
WO-2004072156-A2 SURFACE PREPARATION OF RUBBER FOR COATINGS OR BONDING LORD CORPORATION (US) 2004-08-26 WO disclosed
US-20040157983-A1 Surface preparation of rubber for coatings or bonding LORD CORPORATION 2004-08-12 US disclosed
US-4762589-A Method of making a tubular rubber product having a polyamide or polyester resin layer BRIDGESTONE CORPORATION (JP) 1988-08-09 US disclosed
US-4657285-A Tubular rubber products BRIDGESTONE CORPORATION (JP) 1987-04-14 US disclosed
US-4591618-A HIGH STRENGTH BONDING AGENTS BRIDGESTONE TIRE CO., LTD. (JP) 1986-05-27 US disclosed
US-4300970-A Method of bonding vulcanized rubber to resin BRIDGESTONE TIRE COMPANY LIMITED (JP) 1981-11-17 US disclosed
US-4117036-A ANAEROBIC CURABILITY, SEALANTS BRIDGESTONE TIRE COMPANY LIMITED (JP) 1978-09-26 US disclosed