SCHEMBL6464356

SCHEMBL6464356

CCCCNC(=O)NS(=O)(=O)c1ccc(-c2ccccc2)cc1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 2/20 0.72
ALDH1A1 P00352 2/20 0.72
LMNA P02545 2/20 0.72
TSHR P16473 2/20 0.72
ALB P02768 1/20 0.72
TDP1 Q9NUW8 1/20 0.72
FBP1 P09467 7/20 0.62
MMP2 P08253 3/20 0.60
MMP9 P14780 3/20 0.60
MMP8 P22894 3/20 0.60
MMP12 P39900 3/20 0.60
MMP14 P50281 3/20 0.60
CYP3A4 P08684 1/20 0.58
THRB P10828 1/20 0.58
NFKB1 P19838 1/20 0.58
HTR2A P28223 1/20 0.58
CYP2C19 P33261 1/20 0.58
ADRA1A P35348 1/20 0.58
SMN1; SMN2 Q16637 1/20 0.58
NPSR1 Q6W5P4 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL184964 0.91 CYP2C9 (0.76) CYP2C9ALDH1A1LMNATSHRALB
Methyl Alcohol SCHEMBL28260710 0.90 CYP2C9 (0.74) CYP2C9ALDH1A1LMNATSHRALB
SCHEMBL11049679 0.87 CYP2C9 (0.69) CYP2C9ALDH1A1LMNATSHRALB
SCHEMBL28534045 0.86 EPHX2 (0.68) CYP2C9ALDH1A1LMNATSHRALB
SCHEMBL19271872 0.86 EPHX2 (0.68) CYP2C9ALDH1A1LMNATSHRALB
SCHEMBL1478625 0.84 CYP2C9 (0.74) CYP2C9ALDH1A1LMNATSHRALB
Tolbutamide SCHEMBL15918 0.84 ALDH1A1 (1.00) CYP2C9ALDH1A1LMNATSHRALB
Tolbutamide SCHEMBL1536920 0.84 ALDH1A1 (1.00) CYP2C9ALDH1A1LMNATSHRALB
Tolbutamide SCHEMBL7551276 0.83 ALDH1A1 (0.97) CYP2C9ALDH1A1LMNATSHRALB
Tolbutamide SCHEMBL11357518 0.83 ALDH1A1 (0.97) CYP2C9ALDH1A1LMNATSHRALB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5449657-A Sulfonyl (thio)ureas NEW OJI PAPER CO., LTD. (JP) 1995-09-12 US claimed
EP-0615859-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1994-09-21 EP claimed
US-20050106491-A1 Heat sensitive recording material CIBA SPECIALTY CHEMICALS CORP. 2005-05-19 US disclosed
US-6740465-B2 MULTILAYER; TRANSPARENT SUPPORT; HEAT SENSITIVE ELEMENT AND RELEASE AGENT SIPIX IMAGING, INC. 2004-05-25 US disclosed
EP-1289768-A2 IMAGING MEDIA CONTAINING HEAT DEVELOPABLE PHOTOSENSITIVE MICROCAPSULES Sipix Imaging, Inc. (US) 2003-03-12 EP disclosed
US-20020155372-A1 Imaging media containing heat developable photosensitive microcapsules SIPIX IMAGING, INC. 2002-10-24 US disclosed
WO-2001092024-A2 IMAGING MEDIA CONTAINING HEAT DEVELOPABLE PHOTOSENSITIVE MICROCAPSULES SIPIX IMAGING, INC. (US) 2001-12-06 WO disclosed
US-5449657-A Sulfonyl (thio)ureas NEW OJI PAPER CO., LTD. (JP) 1995-09-12 US disclosed
EP-0615859-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1994-09-21 EP disclosed