Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | RPS6KB2 | Q9UBS0 | 1/20 | 0.36 |
| ▸ | CCNC | P24863 | 1/20 | 0.34 |
| ▸ | CDK8 | P49336 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14607653 | 0.82 | KDM4E (0.44) | KDM4EPOLBALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL14274957 | 0.79 | KDM4E (0.39) | KDM4EPOLBALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL135250 | 0.78 | HDAC6 (0.38) | KDM4EPOLBHPGDSMN1; SMN2NPC1 | |
| SCHEMBL7955398 | 0.77 | S1PR1 (0.34) | RPS6KB2NPC1RAB9APPARGPPARA | |
| SCHEMBL7247782 | 0.77 | CNR1 (0.39) | KDM4EPOLBALDH1A1HPGDHSD17B10 | |
| SCHEMBL3297999 | 0.76 | KDM4E (0.44) | KDM4EPOLBALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL6470277 | 0.76 | KDM4E (0.44) | KDM4EPOLBALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL21310184 | 0.74 | KDM4E (0.44) | KDM4EPOLBALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL3016143 | 0.73 | EPHX2 (0.37) | ALDH1A1TDP1 | |
| SCHEMBL27368716 | 0.72 | KDM4E (0.46) | KDM4EPOLBALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050106491-A1 | Heat sensitive recording material | CIBA SPECIALTY CHEMICALS CORP. | 2005-05-19 | — | — | US | disclosed |