Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | IDH1 | O75874 | 5/20 | 0.34 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | MLYCD | O95822 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | RPS6KB2 | Q9UBS0 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5693442 | 0.78 | FFAR4 (0.40) | IDH1FFAR4PPARDPPARANPC1 | |
| SCHEMBL6464710 | 0.77 | KDM4E (0.40) | PPARGPPARANPC1RAB9ARPS6KB2 | |
| SCHEMBL768820 | 0.75 | GAA (0.41) | S1PR1IDH1MEN1KMT2AMCHR1 | |
| SCHEMBL29353898 | 0.75 | GAA (0.41) | S1PR1IDH1MEN1KMT2AMCHR1 | |
| SCHEMBL135250 | 0.74 | HDAC6 (0.38) | PPARGPPARANPC1RAB9A | |
| SCHEMBL7955396 | 0.72 | FFAR4 (0.38) | IDH1FFAR4PPARDPPARACNR1 | |
| SCHEMBL14462662 | 0.71 | PPARA (0.45) | IDH1FFAR4PPARGPPARDPPARA | |
| SCHEMBL7247782 | 0.71 | CNR1 (0.39) | CNR1CNR2RPS6KB2KMT2A | |
| SCHEMBL9491691 | 0.71 | PPARA (0.47) | FFAR4PPARGPPARDPPARAMLYCD | |
| SCHEMBL1886068 | 0.71 | PPARD (0.36) | S1PR1IDH1PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6271377-B1 | Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith | CIBA SPECIALTY CHEMICALS CORPORATION | 2001-08-07 | — | — | US | disclosed |