SCHEMBL6464765

SCHEMBL6464765

CC(C)(C)NCC(O)c1ccc(O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 4/20 0.68
ADRB2 P07550 3/20 0.68
CYP2C9 P11712 2/20 0.68
TSHR P16473 2/20 0.68
LMNA P02545 2/20 0.68
CASP7 P55210 2/20 0.68
KMT2A Q03164 2/20 0.68
CYP3A4 P08684 1/20 0.68
BLM P54132 2/20 0.63
SMN1; SMN2 Q16637 2/20 0.63
KDM4E B2RXH2 2/20 0.63
TDP1 Q9NUW8 2/20 0.63
ALDH1A1 P00352 1/20 0.63
HTR1A P08908 1/20 0.63
THPO P40225 1/20 0.63
NMUR2 Q9GZQ4 1/20 0.63
TAAR1 Q96RJ0 1/20 0.63
CYP1A2 P05177 1/20 0.59
CYP2D6 P10635 1/20 0.59
NFKB1 P19838 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30534867 1.00 HIF1A (0.68) HIF1AADRB2CYP2C9TSHRLMNA
Hydrochloric Acid SCHEMBL6456085 0.98 HIF1A (0.66) HIF1AADRB2CYP2C9TSHRLMNA
SCHEMBL2298032 0.83 ADRB2 (0.56) HIF1AADRB2CYP2C9TSHRLMNA
SCHEMBL20687559 0.83 ADRB2 (0.56) HIF1AADRB2CYP2C9TSHRLMNA
SCHEMBL2295573 0.83 ADRB2 (0.56) HIF1AADRB2CYP2C9TSHRLMNA
SCHEMBL2293172 0.83 ADRB2 (0.56) HIF1AADRB2CYP2C9TSHRLMNA
SCHEMBL2299015 0.83 ADRB2 (0.56) HIF1AADRB2CYP2C9TSHRLMNA
SCHEMBL2294136 0.83 ADRB2 (0.58) HIF1AADRB2CYP2C9TSHRLMNA
SCHEMBL10484862 0.83 ADRB2 (0.56) HIF1AADRB2CYP2C9TSHRLMNA
SCHEMBL2295878 0.83 ADRB2 (0.58) HIF1AADRB2CYP2C9TSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111721845-B Synchronous detection method for five related substances of compound ipratropium bromide solution for inhalation 鲁南制药集团股份有限公司 2023-08-15 CN claimed
CN-111721845-A Synchronous detection method for five related substances of compound ipratropium bromide solution for inhalation 鲁南制药集团股份有限公司 2020-09-29 CN claimed
US-20190119196-A1 COMPOUNDS FOR THE TREATMENT OF HYPERGLYCAEMIA ATROGI AB (SE) 2019-04-25 US claimed
EP-3426239-A1 COMPOUNDS FOR THE TREATMENT OF HYPERGLYCAEMIA Atrogi AB (SE) 2019-01-16 EP claimed
WO-2017153737-A1 COMPOUNDS FOR THE TREATMENT OF HYPERGLYCAEMIA ATROGI AB (SE) 2017-09-14 WO claimed
EP-4676481-A1 COMBINATION OF BETA-2-ADRENERGIC RECEPTOR AGONISTS AND GLP-1 RECEPTOR AGONISTS FOR USE IN TREATING HYPERGLYCAEMIA Atrogi AB (SE) 2026-01-14 EP disclosed
EP-4665321-A1 COMBINATIONS OF BETA 2-ADRENERGIC RECEPTOR AGONISTS AND METFORMIN FOR USE IN TREATING OBESITY AND REDUCING BODY FAT Atrogi AB (SE) 2025-12-24 EP disclosed
EP-4651867-A1 BETA 2-ADRENERGIC RECEPTOR AGONISTS FOR TREATMENT OR PREVENTION OF MUSCLE WASTING Atrogi AB (SE) 2025-11-26 EP disclosed
WO-2024184408-A1 COMBINATION OF BETA-2-ADRENERGIC RECEPTOR AGONISTS AND GLP-1 RECEPTOR AGONISTS FOR USE IN TREATING HYPERGLYCAEMIA ATROGI AB (SE) 2024-09-12 WO disclosed
WO-2024170727-A1 COMBINATIONS OF BETA 2-ADRENERGIC RECEPTOR AGONISTS AND METFORMIN FOR USE IN TREATING OBESITY AND REDUCING BODY FAT ATROGI AB (SE) 2024-08-22 WO disclosed
WO-2024153813-A1 BETA 2-ADRENERGIC RECEPTOR AGONISTS FOR TREATMENT OR PREVENTION OF MUSCLE WASTING ATROGI AB (SE) 2024-07-25 WO disclosed
CN-111721845-B Synchronous detection method for five related substances of compound ipratropium bromide solution for inhalation 鲁南制药集团股份有限公司 2023-08-15 CN disclosed
US-20190119196-A1 COMPOUNDS FOR THE TREATMENT OF HYPERGLYCAEMIA ATROGI AB (SE) 2019-04-25 US disclosed
WO-2019053428-A1 BETA-HYDROXYETHYLAMINES FOR USE IN THE TREATMENT OR PREVENTION OF NON-ALCOHOLIC FATTY LIVER DISEASES ATROGI AB (SE) 2019-03-21 WO disclosed
WO-2019053428-A1 BETA-HYDROXYETHYLAMINES FOR USE IN THE TREATMENT OR PREVENTION OF NON-ALCOHOLIC FATTY LIVER DISEASES ATROGI AB (SE) 2019-03-21 WO disclosed
EP-3426239-A1 COMPOUNDS FOR THE TREATMENT OF HYPERGLYCAEMIA Atrogi AB (SE) 2019-01-16 EP disclosed
WO-2017153737-A1 COMPOUNDS FOR THE TREATMENT OF HYPERGLYCAEMIA ATROGI AB (SE) 2017-09-14 WO disclosed
WO-2017153737-A1 COMPOUNDS FOR THE TREATMENT OF HYPERGLYCAEMIA ATROGI AB (SE) 2017-09-14 WO disclosed
WO-2005108381-A1 SYNTHESIS AND USES OF SYNEPHRINE DERIVATIVES SYNTECH (SSPF) INTERNATIONAL INC. (US) 2005-11-17 WO disclosed
US-20050250944-A1 Synthesis and uses of synephrine derivatives SYNTECH (SSPF) INTERNATIONAL INC. 2005-11-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050250944-A1 Synthesis and uses of synephrine derivatives ADRB3, ADRB2, ADRB1 HIF1A 3823/4885ADRB2 2/4885CYP2C9 2074/4885
US-20190119196-A1 COMPOUNDS FOR THE TREATMENT OF HYPERGLYCAEMIA SLC5A2, SLC5A1, SLC2A2 HIF1A 527/4885ADRB2 229/4885CYP2C9 2173/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.