SCHEMBL646483

SCHEMBL646483

O=S(=O)(O)c1ccccc1OC(Cl)(Cl)Cl

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MYC P01106 1/20 0.37
▸ ELANE P08246 1/20 0.36
▸ TSHR P16473 1/20 0.35
▸ SMN1; SMN2 Q16637 1/20 0.35
▸ TTR P02766 2/20 0.35
▸ HSD11B1 P28845 1/20 0.35
▸ HSD17B3 P37058 1/20 0.35
▸ HTR6 P50406 1/20 0.34
▸ SLC22A12 Q96S37 3/20 0.33
▸ KMT2A Q03164 2/20 0.33
▸ MEN1 O00255 1/20 0.33
▸ ESR1 P03372 1/20 0.33
▸ GAA P10253 1/20 0.33
▸ ESR2 Q92731 1/20 0.33
▸ FABP4 P15090 1/20 0.33
▸ CCNA2 P20248 1/20 0.33
▸ CDK2 P24941 1/20 0.33
▸ MAPK14 Q16539 1/20 0.33
▸ HSD17B10 Q99714 2/20 0.32
▸ ALDH1A1 P00352 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL645001 0.81 ALPL (0.46) ELANEHTR6SLC22A12GAAALDH1A1
SCHEMBL15457977 0.80 HSD17B10 (0.38) MYCELANETSHRSMN1; SMN2TTR
Hydrochloric Acid SCHEMBL27729259 0.79 ALPL (0.45) ELANEHTR6SLC22A12GAAALPL
Hydrochloric Acid SCHEMBL28291841 0.79 MYC (0.40) MYCELANETSHRSMN1; SMN2TTR
SCHEMBL11752201 0.78 MYC (0.40) MYCELANETSHRSMN1; SMN2TTR
SCHEMBL5698446 0.77 MYC (0.42) MYCELANETSHRSMN1; SMN2TTR
SCHEMBL8983185 0.77 MYC (0.42) MYCELANETSHRSMN1; SMN2TTR
SCHEMBL6160456 0.75 SMN1; SMN2 (0.46) MYCELANETSHRSMN1; SMN2TTR
SCHEMBL4962913 0.75 MYC (0.41) MYCELANETSHRSMN1; SMN2TTR
SCHEMBL28521154 0.75 MYC (0.41) MYCELANETSHRSMN1; SMN2TTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4536395-A1 CLAY COMPOSITE SUPPORT-ACTIVATORS AND CATALYST COMPOSITIONS Formosa Plastics Corporation, U.S.A. (US) 2025-04-16 — — EP disclosed
CN-119278097-A Clay complex support-activator and catalyst composition 美国台塑公司 2025-01-07 — — CN disclosed
WO-2023239560-A1 CLAY COMPOSITE SUPPORT-ACTIVATORS AND CATALYST COMPOSITIONS FORMOSA PLASTICS CORPORATON, U.S.A. (US) 2023-12-14 — — WO disclosed
US-20230399420-A1 CLAY COMPOSITE SUPPORT-ACTIVATORS AND CATALYST COMPOSITIONS FORMOSA PLASTICS CORPORATION, U.S.A. (US) 2023-12-14 — — US disclosed
EP-3239190-B1 POLYMERIZATION CATALYSTS FOR PRODUCING POLYMERS WITH LOW LEVELS OF LONG CHAIN BRANCHING CHEVRON PHILLIPS CHEMICAL CO LP (US) 2020-01-29 — — EP disclosed
EP-2193151-B1 POLYMERIZATION CATALYSTS FOR PRODUCING POLYMERS WITH HIGH COMONOMER INCORPORATION CHEVRON PHILLIPS CHEMICAL CO LP (US) 2019-04-03 — — EP disclosed
EP-3239190-A2 POLYMERIZATION CATALYSTS FOR PRODUCING POLYMERS WITH LOW LEVELS OF LONG CHAIN BRANCHING Chevron Phillips Chemical Company LP (US) 2017-11-01 — — EP disclosed
EP-1984408-B1 POLYMERIZATION CATALYSTS FOR PRODUCING POLYMERS WITH LOW LEVELS OF LONG CHAIN BRANCHING CHEVRON PHILLIPS CHEMICAL CO LP (US) 2017-07-26 — — EP disclosed
EP-2201047-B1 POLYMERIZATION CATALYSTS FOR PRODUCING POLYMERS WITH LOW MELT ELASTICITY CHEVRON PHILLIPS CHEMICAL CO (US) 2016-05-04 — — EP disclosed
US-8637691-B2 Polymerization catalysts for producing polymers with low melt elasticity CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2014-01-28 — — US disclosed
US-20090281342-A1 POLYMERIZATION CATALYSTS FOR PRODUCING HIGH MOLECULAR WEIGHT POLYMERS WITH LOW LEVELS OF LONG CHAIN BRANCHING CHEVRON PHILLIPS CHEMICAL COMPANY, LP 2009-11-12 — — US disclosed
US-7576163-B2 Polymerization catalysts for producing polymers with low levels of long chain branching CHEVRON PHILLIPS CHEMICAL COMPANY, LP (US) 2009-08-18 — — US disclosed
US-7517939-B2 Polymerization catalysts for producing high molecular weight polymers with low levels of long chain branching CHEVRON PHILLIPS CHEMICAL COMPANY, LP (US) 2009-04-14 — — US disclosed
US-20090088537-A1 Polymerization catalysts for producing polymers with high comonomer incorporation CHEVRON PHILLIPS CHEMICAL COMPANY LP 2009-04-02 — — US disclosed
US-20090088543-A1 Polymerization catalysts for producing polymers with low melt elasticity CHEVRON PHILLIPS CHEMICAL COMPANY LP 2009-04-02 — — US disclosed
EP-2010577-A2 POLYMERIZATION CATALYSTS FOR PRODUCING POLYMERS WITH LOW LEVELS OF LONG CHAIN BRANCHING Chevron Phillips Chemical Company LP (US) 2009-01-07 — — EP disclosed
WO-2007115093-A2 POLYMERIZATION CATALYSTS FOR PRODUCING POLYMERS WITH LOW LEVELS OF LONG CHAIN BRANCHING CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2007-10-11 — — WO disclosed
US-20070232483-A1 Polymerization catalysts for producing polymers with low levels of long chain branching CHEVRON PHILLIPS CHEMICAL COMPANY, L.P. 2007-10-04 — — US disclosed
US-20070197374-A1 Dual metallocene catalysts for polymerization of bimodal polymers CHEVRON PHILLIPS CHEMICAL COMPANY, L.P. 2007-08-23 — — US disclosed
US-20070179044-A1 Polymerization catalysts for producing high molecular weight polymers with low levels of long chain branching CHEVRON PHILLIPS CHEMICAL COMPANY, L.P. 2007-08-02 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090281342-A1 POLYMERIZATION CATALYSTS FOR PRODUCING HIGH MOLECULAR WEIGHT POLYMERS WITH LOW LEVELS OF LONG CHAIN BRANCHING PARG, PARP1, PCNA MYC 2263/4885ELANE 518/4885TSHR 4768/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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