Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4A | O75164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3798888 | 0.88 | KDM4A (0.40) | KDM4AL3MBTL1LMNAKDM4ENAMPT | |
| SCHEMBL2557942 | 0.87 | HTT (0.49) | LMNAKDM4EHTTNPSR1MAPT | |
| SCHEMBL6468245 | 0.82 | KDM4A (0.42) | KDM4AL3MBTL1LMNAKDM4ENAMPT | |
| SCHEMBL3796522 | 0.81 | CA1 (0.39) | KDM4AL3MBTL1LMNAKDM4ENAMPT | |
| SCHEMBL3586130 | 0.80 | KDM4A (0.40) | KDM4AL3MBTL1LMNAKDM4ENAMPT | |
| SCHEMBL3583656 | 0.78 | KDM4A (0.40) | KDM4AL3MBTL1LMNAKDM4ENAMPT | |
| SCHEMBL24387623 | 0.77 | MAPKAPK2 (0.42) | KDM4AL3MBTL1LMNAKDM4EHTT | |
| SCHEMBL21129147 | 0.75 | HDAC1 (0.39) | KDM4AL3MBTL1LMNAKDM4ENAMPT | |
| SCHEMBL3508704 | 0.75 | KMT2A (0.48) | L3MBTL1LMNACA1CA2MAPT | |
| SCHEMBL2552259 | 0.75 | HTT (0.50) | LMNAKDM4EHTTNPSR1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012054510-A1 | OXADIAZOLE COMPOUNDS WHICH INHIBIT BETA-SECRETASE ACTIVITY AND METHODS OF USE THEREOF | COMENTIS, INC. (US) | 2012-04-26 | — | — | WO | disclosed |