SCHEMBL6464901

SCHEMBL6464901

CCc1ccccc1C(=O)OOC(=O)c1ccccc1CC

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.52
ALDH1A1 P00352 6/20 0.49
LMNA P02545 4/20 0.49
TDP1 Q9NUW8 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
UTS2R Q9UKP6 1/20 0.44
HSD17B10 Q99714 1/20 0.44
TP53 P04637 1/20 0.44
CYP3A4 P08684 1/20 0.44
MAPK1 P28482 1/20 0.44
HTT P42858 1/20 0.44
CLCN2 P51788 1/20 0.43
GABRA1 P14867 1/20 0.43
GABRB2 P47870 1/20 0.43
F2 P00734 1/20 0.43
SCN1A P35498 1/20 0.42
SCN2A Q99250 1/20 0.42
SCN3A Q9NY46 1/20 0.42
KDM4E B2RXH2 1/20 0.41
GLA P06280 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8438433 0.92 ALDH1A1 (0.50) TSHRALDH1A1LMNATDP1L3MBTL1
SCHEMBL2473946 0.88 TSHR (0.50) TSHRALDH1A1LMNATDP1L3MBTL1
SCHEMBL739158 0.87 TSHR (0.52) TSHRALDH1A1LMNATDP1L3MBTL1
SCHEMBL6567550 0.86 ESR1 (0.50) TSHRALDH1A1LMNATDP1HSD17B10
SCHEMBL6462771 0.86 ALDH1A1 (0.53) TSHRALDH1A1LMNATDP1L3MBTL1
SCHEMBL15972632 0.85 ALDH1A1 (0.47) TSHRALDH1A1LMNATDP1L3MBTL1
SCHEMBL156281 0.85 ALDH1A1 (0.66) TSHRALDH1A1LMNAHSD17B10HTT
SCHEMBL1532511 0.85 TSHR (0.50) TSHRALDH1A1LMNATDP1L3MBTL1
Ammonia Solution, Strong SCHEMBL28026712 0.84 ALDH1A1 (0.51) TSHRALDH1A1LMNATDP1L3MBTL1
SCHEMBL28167723 0.84 TSHR (0.42) TSHRALDH1A1LMNATDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6951904-B1 Process for increasing the melt strength of polypropylene POLYMERS AUSTRALIA PTY LIMITED (AU) 2005-10-04 US claimed
EP-1080148-A4 PROCESS FOR INCREASING THE MELT STRENGTH OF POLYPROPYLENE POLYMERS AUSTRALIA PTY LTD (AU) 2003-02-05 EP claimed
EP-1080148-A1 PROCESS FOR INCREASING THE MELT STRENGTH OF POLYPROPYLENE Polymers Australia PTY Limited (AU) 2001-03-07 EP claimed
WO-1999036466-A1 PROCESS FOR INCREASING THE MELT STRENGTH OF POLYPROPYLENE POLYMERS AUSTRALIA PTY LIMITED (AU) 1999-07-22 WO claimed
CN-114127137-A Acrylic rubber bale with excellent strength characteristic and processability 日本瑞翁株式会社 2022-03-01 CN disclosed
US-6951904-B1 Process for increasing the melt strength of polypropylene POLYMERS AUSTRALIA PTY LIMITED (AU) 2005-10-04 US disclosed
EP-1080148-A4 PROCESS FOR INCREASING THE MELT STRENGTH OF POLYPROPYLENE POLYMERS AUSTRALIA PTY LTD (AU) 2003-02-05 EP disclosed
EP-1080148-A1 PROCESS FOR INCREASING THE MELT STRENGTH OF POLYPROPYLENE Polymers Australia PTY Limited (AU) 2001-03-07 EP disclosed
WO-1999036466-A1 PROCESS FOR INCREASING THE MELT STRENGTH OF POLYPROPYLENE POLYMERS AUSTRALIA PTY LIMITED (AU) 1999-07-22 WO disclosed
EP-0019198-A1 Process for preparing polymers of vinyl chloride, composition for coating polymerization vessels and polymerization vessel coated therewith HOECHST AKTIENGESELLSCHAFT (DE) 1980-11-26 EP disclosed
EP-0019197-A1 Process for preparing polymers of vinyl chloride, composition for coating polymerization vessels, and polymerization vessel coated therewith HOECHST AKTIENGESELLSCHAFT (DE) 1980-11-26 EP disclosed