SCHEMBL8438433

SCHEMBL8438433

CCc1ccccc1C(=O)OOC

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.50
LMNA P02545 3/20 0.50
TSHR P16473 7/20 0.48
HTT P42858 1/20 0.45
TDP1 Q9NUW8 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
UTS2R Q9UKP6 1/20 0.43
KDM4E B2RXH2 1/20 0.42
GLA P06280 1/20 0.42
HIF1A Q16665 1/20 0.42
HSD17B10 Q99714 2/20 0.42
TP53 P04637 1/20 0.42
CYP3A4 P08684 1/20 0.42
MAPK1 P28482 1/20 0.42
CFTR P13569 1/20 0.41
CLCN2 P51788 1/20 0.41
KMT2A Q03164 1/20 0.41
HPGD P15428 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6464901 0.92 TSHR (0.52) ALDH1A1LMNATSHRHTTTDP1
SCHEMBL28123004 0.86 HTT (0.54) ALDH1A1LMNATSHRHTTTDP1
SCHEMBL156281 0.86 ALDH1A1 (0.66) ALDH1A1LMNATSHRHTTKDM4E
SCHEMBL27865356 0.85 TSHR (0.58) ALDH1A1LMNATSHRTDP1L3MBTL1
SCHEMBL2473946 0.85 TSHR (0.50) ALDH1A1LMNATSHRHTTTDP1
SCHEMBL739158 0.83 TSHR (0.52) ALDH1A1LMNATSHRHTTTDP1
SCHEMBL28469248 0.83 GABRA1 (0.41) ALDH1A1LMNATSHRHTTTDP1
SCHEMBL27460123 0.83 TSHR (0.53) ALDH1A1LMNATSHRHTTTDP1
SCHEMBL15972632 0.82 ALDH1A1 (0.47) ALDH1A1LMNATSHRHTTTDP1
SCHEMBL1532511 0.82 TSHR (0.50) ALDH1A1LMNATSHRHTTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109096425-A A kind of catalyst and olefine polymerizing process for olefinic polymerization 中国石油化工股份有限公司 2018-12-28 CN claimed
CN-110382574-A Heterophasic propylene polymeric material and Propenes resin composition 住友化学株式会社 2019-10-25 CN disclosed
CN-108341902-A Catalytic component for vinyl polymerization and preparation method thereof and catalyst for vinyl polymerization 中国石油化工股份有限公司 2018-07-31 CN disclosed
CN-105683278-B The manufacturing method of stabilized polymer 株式会社ADEKA 2018-06-15 CN disclosed
CN-107935828-A A kind of method that aromatic aldehyde is prepared by methylbenzenes high selectivity 浙江大学 2018-04-20 CN disclosed
CN-107922347-A New imide derivative and its purposes as medicine 田边三菱制药株式会社 2018-04-17 CN disclosed
CN-106414520-A Procatalyst for polymerization of olefins comprising monoester and amidobenzoate internal donor SABIC环球技术有限责任公司 2017-02-15 CN disclosed
CN-104203991-B Family's electric material manufacture method with automotive interior trim material olefin resin composition 株式会社ADEKA 2016-07-06 CN disclosed
CN-105683278-A Method for producing stabilized polymer 株式会社ADEKA 2016-06-15 CN disclosed
CN-103403036-B The manufacture method of laminated film and application component resin combination ADEKA CORP. (JP) 2015-11-25 CN disclosed
US-5859143-A BLOCK COPOLYMERIZATION REACTION IN PRESENCE OF HYDROGEN AND STEREOSPECIFIC CATALYST CONTAINING COMPOUNDS OF MAGNESIUM, TITANIUM, HALOGEN, ORGANOALUMINUM AND ELECTRON DONOR MITSUBISHI CHEMICAL CORPORATION (JP) 1999-01-12 US disclosed
CN-1051736-A OLEFIN POLYMERIZATION CATALYSIS SHELL INT RESEARCH (NL) 1991-05-29 CN disclosed
EP-0310040-A1 Process for reducing odor in isotactic polypropylene UNION CARBIDE CORPORATION (US) 1989-04-05 EP disclosed