Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSIP1 | O75475 | 1/20 | 0.56 |
| ▸ | HSD11B1 | P28845 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 2/20 | 0.41 |
| ▸ | MMP2 | P08253 | 2/20 | 0.41 |
| ▸ | MMP13 | P45452 | 2/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22218952 | 0.83 | PSIP1 (0.54) | PSIP1HSD11B1ALDH1A1HSD17B10TDP1 | |
| SCHEMBL2446368 | 0.83 | PSIP1 (0.60) | PSIP1HSD11B1ALDH1A1KMT2AMEN1 | |
| SCHEMBL7296389 | 0.81 | PSIP1 (0.58) | PSIP1HSD11B1ALDH1A1KMT2AMEN1 | |
| SCHEMBL7348328 | 0.79 | HSD11B1 (0.56) | PSIP1HSD11B1ALDH1A1KMT2AMEN1 | |
| SCHEMBL19248406 | 0.79 | PSIP1 (0.56) | PSIP1HSD11B1ALDH1A1KMT2AMEN1 | |
| SCHEMBL1540325 | 0.79 | PSIP1 (0.56) | PSIP1HSD11B1ALDH1A1KMT2AMEN1 | |
| SCHEMBL1540327 | 0.79 | PSIP1 (0.56) | PSIP1HSD11B1ALDH1A1KMT2AMEN1 | |
| SCHEMBL1527680 | 0.79 | HSD11B1 (0.56) | PSIP1HSD11B1ALDH1A1KMT2AMEN1 | |
| SCHEMBL2446758 | 0.78 | PSIP1 (0.59) | PSIP1HSD11B1ALDH1A1KMT2AMEN1 | |
| SCHEMBL11187026 | 0.76 | PSIP1 (0.47) | PSIP1HSD11B1ALDH1A1HSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050042676-A1 | Characterising polypeptides | ELECTROPHORETICS LIMITED (GB) | 2005-02-24 | — | — | US | disclosed |
| EP-1397505-A2 | CHARACTERISING POLYPEPTIDES | Xzillion GmbH & CO.KG (DE) | 2004-03-17 | — | — | EP | disclosed |
| EP-1267170-A1 | Method for characterising polypeptides | Xzillion GmbH & CO.KG (DE) | 2002-12-18 | — | — | EP | disclosed |
| WO-2002099124-A2 | CHARACTERISING POLYPEPTIDES | XZILLION GMBH & CO. KG (DE) | 2002-12-12 | — | — | WO | disclosed |