Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX1 | Q9Y5S8 | 3/20 | 0.81 |
| ▸ | SMPD3 | Q9NY59 | 4/20 | 0.79 |
| ▸ | MAPT | P10636 | 7/20 | 0.63 |
| ▸ | TP53 | P04637 | 4/20 | 0.63 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | HPGD | P15428 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.56 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.56 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.56 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.56 |
| ▸ | RAF1 | P04049 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6466286 | 0.89 | NOX1 (0.72) | NOX1SMPD3MAPTTP53MEN1 | |
| SCHEMBL6466417 | 0.88 | NOX1 (0.79) | NOX1SMPD3MAPTTP53MAPK13 | |
| SCHEMBL6691401 | 0.88 | SMPD3 (1.00) | NOX1SMPD3MAPTTP53MEN1 | |
| SCHEMBL6465425 | 0.88 | SMPD3 (0.76) | NOX1SMPD3MAPTTP53MEN1 | |
| SCHEMBL5676205 | 0.86 | NOX1 (0.76) | NOX1SMPD3MAPTTP53CYP1A2 | |
| SCHEMBL10588313 | 0.85 | NOX1 (0.74) | NOX1SMPD3MAPTTP53MEN1 | |
| SCHEMBL6469484 | 0.84 | NOX1 (0.88) | NOX1SMPD3MAPTTP53MAPK13 | |
| SCHEMBL6466475 | 0.83 | NOX1 (0.71) | NOX1SMPD3MAPTTP53MAPK13 | |
| SCHEMBL15400824 | 0.83 | NOX1 (0.85) | NOX1SMPD3MAPTTP53MEN1 | |
| SCHEMBL8008805 | 0.83 | NOX1 (0.85) | NOX1SMPD3MAPTTP53MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050203155-A1 | Imidazole compounds and human cellular proteins casein kinase I alpha, delta and epsilon as targets for medical intervention against Hepatitis C Virus infections | AXXIMA PHARMACEUTICAL AG. (DE) | 2005-09-15 | — | — | US | claimed |
| EP-1532118-A2 | IMIDAZOLE COMPOUNDS FOR THE TREATMENT OF HEPATITIS C VIRUS INFECTIONS | Axxima Pharmaceuticals Aktiengesellschaft (DE) | 2005-05-25 | — | — | EP | claimed |
| WO-2004005264-A2 | IMIDAZOLE COMPOUNDS FOR THE TREATMENT OF HEPATITIS C VIRUS INFECTIONS | AXXIMA PHARMACEUTICALS AG (DE) | 2004-01-15 | — | — | WO | claimed |
| US-20240000821-A1 | CHEMICAL INHIBITORS AGAINST KINASES TO BLOCK TELOMERE ELONGATION IN CANCER | UNIV JOHNS HOPKINS (US) | 2024-01-04 | — | — | US | disclosed |
| US-20200078387-A1 | CHEMICAL INHIBITORS AGAINST KINASES TO BLOCK TELOMERE ELONGATION IN CANCER | THE JOHNS HOPKINS UNIVERSITY | 2020-03-12 | — | — | US | disclosed |
| WO-2018112342-A1 | CHEMICAL INHIBITORS AGAINST KINASES TO BLOCK TELOMERE ELONGATION IN CANCER | THE JOHNS HOPKINS UNIVERSITY (US) | 2018-06-21 | — | — | WO | disclosed |
| US-20050203155-A1 | Imidazole compounds and human cellular proteins casein kinase I alpha, delta and epsilon as targets for medical intervention against Hepatitis C Virus infections | AXXIMA PHARMACEUTICAL AG. (DE) | 2005-09-15 | — | — | US | disclosed |
| EP-1532118-A2 | IMIDAZOLE COMPOUNDS FOR THE TREATMENT OF HEPATITIS C VIRUS INFECTIONS | Axxima Pharmaceuticals Aktiengesellschaft (DE) | 2005-05-25 | — | — | EP | disclosed |
| WO-2004005264-A2 | IMIDAZOLE COMPOUNDS FOR THE TREATMENT OF HEPATITIS C VIRUS INFECTIONS | AXXIMA PHARMACEUTICALS AG (DE) | 2004-01-15 | — | — | WO | disclosed |
| EP-0603953-B1 | Use of 4' of 5'-hydroxy and 4'- or 5'-alkoxy-substituted electron transfer agents in compositions, elements, test kits and analytical methods | JOHNSON & JOHNSON CLIN DIAG (US) | 1999-02-17 | — | — | EP | disclosed |
| EP-0462644-B1 | Biologically active reagents prepared from carboxy-containing polymer, analytical element and methods of use | JOHNSON & JOHNSON CLIN DIAG (US) | 1995-10-18 | — | — | EP | disclosed |
| WO-1990009594-A2 | WASH COMPOSITION, TEST KIT AND THEIR USE TO DETERMINE A HERPES SIMPLEX VIRAL ANTIGEN | EASTMAN KODAK COMPANY (US) | 1990-08-23 | — | — | WO | disclosed |
| EP-0382519-A2 | Extraction composition, test kit and their use to extract or determine herpes simplex viral antigen | EASTMAN KODAK COMPANY (US) | 1990-08-16 | — | — | EP | disclosed |
| EP-0370694-A2 | Diagnostic kit and method using a solid phase capture means for detecting nucleic acids | EASTMAN KODAK COMPANY (US) | 1990-05-30 | — | — | EP | disclosed |
| EP-0363110-A2 | High pH extraction composition and its use to determine a chlamydial, gonococcal or herpes antigen | Johnson & Johnson Clinical Diagnostics, Inc. (US) | 1990-04-11 | — | — | EP | disclosed |
| EP-0363109-A2 | Determination of a chlamydial or gonococcal antigen using a positively-charged ionically binding support | Johnson & Johnson Clinical Diagnostics, Inc. (US) | 1990-04-11 | — | — | EP | disclosed |
| EP-0363090-A2 | Diagnostic test kit and method for determination of chlamydial or gonococcal antigens using a microporous membrane | Johnson & Johnson Clinical Diagnostics, Inc. (US) | 1990-04-11 | — | — | EP | disclosed |
| EP-0363106-A2 | Use of cationic surfactant to extract the chlamydial major outer membrane protein antigen | Johnson & Johnson Clinical Diagnostics, Inc. (US) | 1990-04-11 | — | — | EP | disclosed |
| EP-0363108-A2 | Wash solution containing a cationic surfactant and its use in chlamydial and gonococcal determinations | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1990-04-11 | — | — | EP | disclosed |
| EP-0363089-A2 | Use of a protease in the extraction of chlamydial, gonococcal and herpes antigens | Johnson & Johnson Clinical Diagnostics, Inc. (US) | 1990-04-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050203155-A1 | Imidazole compounds and human cellular proteins casein kinase I alpha, delta and epsilon as targets for medical intervention against Hepatitis C Virus infections | CSNK1G1, CSNK1E, CSNK1D | NOX1 2876/4885SMPD3 3746/4885MAPT 1480/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.