Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | PKM | P14618 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | IMPDH2 | P12268 | 5/20 | 0.42 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL475579 | 0.94 | KDM4E (0.43) | EDNRAATMKDM4EPKMLMNA | |
| SCHEMBL4245857 | 0.85 | EDNRA (0.55) | EDNRAKDM4EPKMLMNAALDH1A1 | |
| SCHEMBL64372 | 0.84 | PKM (0.55) | KDM4EPKMLMNAALDH1A1NPC1 | |
| SCHEMBL4872480 | 0.81 | GPR119 (0.39) | EDNRAKDM4EPKMLMNAALDH1A1 | |
| SCHEMBL9454172 | 0.81 | CHRM2 (0.45) | EDNRAATMKDM4EPKMLMNA | |
| SCHEMBL12490494 | 0.80 | GPR119 (0.47) | EDNRAATMKDM4ELMNAALDH1A1 | |
| SCHEMBL9454214 | 0.75 | KDM4E (0.58) | EDNRAATMKDM4EPKMLMNA | |
| SCHEMBL1949259 | 0.74 | CA1 (0.62) | KDM4ELMNAALDH1A1CA12CA1 | |
| SCHEMBL5156551 | 0.74 | GPR119 (0.37) | KDM4EPKMLMNAALDH1A1NPC1 | |
| SCHEMBL26971054 | 0.74 | MAPK1 (0.51) | KDM4EALDH1A1NPC1RAB9AIMPDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012054510-A1 | OXADIAZOLE COMPOUNDS WHICH INHIBIT BETA-SECRETASE ACTIVITY AND METHODS OF USE THEREOF | COMENTIS, INC. (US) | 2012-04-26 | — | — | WO | disclosed |