Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6501890 | 0.80 | CA12 (0.45) | MEN1KMT2A | |
| SCHEMBL6502508 | 0.79 | KDM4E (0.51) | HPGDKDM4ESMN1; SMN2RAB9ACYP1A2 | |
| SCHEMBL2358907 | 0.77 | SMN1; SMN2 (0.62) | HPGDALOX15KDM4ESMN1; SMN2RAB9A | |
| SCHEMBL2459851 | 0.77 | ALDH1A1 (0.47) | KDM4ESMN1; SMN2RAB9ACYP1A2NPC1 | |
| SCHEMBL10608407 | 0.76 | HTT (0.71) | HPGDALOX15KDM4ESMN1; SMN2RAB9A | |
| Chlorpropham SCHEMBL54464 | 0.75 | HPGD (1.00) | HPGDALOX15KDM4ESMN1; SMN2RAB9A | |
| Chlorpropham SCHEMBL22437601 | 0.75 | HPGD (1.00) | HPGDALOX15KDM4ESMN1; SMN2RAB9A | |
| Chlorpropham SCHEMBL8538082 | 0.75 | HPGD (1.00) | HPGDALOX15KDM4ESMN1; SMN2RAB9A | |
| SCHEMBL10344871 | 0.74 | L3MBTL1 (0.55) | KDM4ERAB9ANPC1MAPTHTT | |
| SCHEMBL15143918 | 0.74 | SMN1; SMN2 (0.79) | HPGDALOX15KDM4ESMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005082414-A2 | CONCOMITANT DRUGS OF A SULFONAMIDE AND ANOTHER THERAPEUTIC AGENT | ASTELLAS PHARMA INC. (JP) | 2005-09-09 | — | — | WO | disclosed |