Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 7/20 | 0.40 |
| ▸ | CDK8 | P49336 | 7/20 | 0.40 |
| ▸ | ICAM1 | P05362 | 4/20 | 0.39 |
| ▸ | SELE | P16581 | 4/20 | 0.39 |
| ▸ | VCAM1 | P19320 | 3/20 | 0.39 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.37 |
| ▸ | PRNP | P04156 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6025930 | 0.86 | CCNC (0.43) | CCNCCDK8ICAM1SELEVCAM1 | |
| SCHEMBL6026223 | 0.82 | STING1 (0.47) | MAPK1ALDH1A1HPGDHSD17B10ABCG2 | |
| SCHEMBL6025626 | 0.80 | ICAM1 (0.41) | ICAM1SELEVCAM1MAPK1HPGD | |
| SCHEMBL6025020 | 0.78 | COMT (0.39) | ICAM1SELEVCAM1MAPK1ALDH1A1 | |
| SCHEMBL6025169 | 0.77 | EDNRA (0.47) | MAPK1ALDH1A1HPGDHTT | |
| SCHEMBL6026202 | 0.76 | KMT2A (0.38) | MAPK1ALDH1A1HPGDHSD17B10ABCG2 | |
| SCHEMBL5215280 | 0.74 | ESR1 (0.43) | CCNCCDK8SERPINE1MAPK1ALDH1A1 | |
| SCHEMBL6025205 | 0.73 | HTR2A (0.39) | — | |
| SCHEMBL6026496 | 0.73 | PIK3CD (0.36) | ICAM1SELEVCAM1MAPK1ALDH1A1 | |
| SCHEMBL6025778 | 0.72 | ALDH1A1 (0.38) | ICAM1SELEVCAM1MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050096350-A1 | Halo substituted benzo[b]thiophenes as therapeutic agents | CONNOLLY MICHAEL K (US) | 2005-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050096350-A1 | Halo substituted benzo[b]thiophenes as therapeutic agents | HCLS1, BRI3BP, BRPF1 | CCNC 2549/4885CDK8 2883/4885ICAM1 4657/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.