SCHEMBL6465976

SCHEMBL6465976

O=C(Nc1ccc(Cc2ccc(NC(=O)NS(=O)(=O)C3CCCCC3)cc2)cc1)NS(=O)(=O)C1CCCCC1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
LMNA P02545 1/20 0.49
RAB9A P51151 5/20 0.48
NPC1 O15118 4/20 0.48
NAMPT P43490 5/20 0.47
EPHX1 P07099 5/20 0.45
EPHX2 P34913 2/20 0.45
SAE1 Q9UBE0 2/20 0.43
UBA2 Q9UBT2 2/20 0.43
GLA P06280 1/20 0.43
CA12 O43570 2/20 0.42
CA1 P00915 2/20 0.42
CA2 P00918 2/20 0.42
CA9 Q16790 2/20 0.42
ALDH1A1 P00352 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
GAA P10253 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8095024 0.84 RAB9A (0.60) MEN1KMT2ALMNARAB9ANPC1
SCHEMBL6466718 0.84 EPHX1 (0.58) MEN1KMT2ALMNARAB9AEPHX1
SCHEMBL8091213 0.82 RAB9A (0.57) MEN1KMT2ARAB9ANPC1EPHX1
SCHEMBL8091184 0.82 RAB9A (0.57) MEN1KMT2ARAB9ANPC1EPHX1
SCHEMBL8083387 0.82 RAB9A (0.57) MEN1KMT2ALMNARAB9ANPC1
SCHEMBL19505872 0.82 ACP1 (0.57) MEN1KMT2ALMNARAB9AEPHX1
SCHEMBL8089942 0.81 RAB9A (0.56) MEN1KMT2ALMNARAB9ANPC1
SCHEMBL8095056 0.77 EPHX2 (0.54) MEN1KMT2ALMNARAB9ANPC1
SCHEMBL8095054 0.77 EPHX2 (0.54) MEN1KMT2ALMNARAB9ANPC1
SCHEMBL6464227 0.77 RORC (0.57) MEN1KMT2ALMNANAMPTCA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050255998-A1 Mixture of colour developers CIBA SPECIALTY CHEMICALS CORP. 2005-11-17 US disclosed
US-20050106491-A1 Heat sensitive recording material CIBA SPECIALTY CHEMICALS CORP. 2005-05-19 US disclosed
EP-1480835-A1 HEAT SENSITIVE RECORDING MATERIAL Ciba SC Holding AG (CH) 2004-12-01 EP disclosed
EP-1480836-A1 MIXTURE OF COLOUR DEVELOPERS Ciba SC Holding AG (CH) 2004-12-01 EP disclosed
WO-2003074284-A1 MIXTURE OF COLOUR DEVELOPERS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-09-12 WO disclosed
WO-2003074285-A1 HEAT SENSITIVE RECORDING MATERIAL CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-09-12 WO disclosed
EP-0604832-B1 Thermosensitive recording material OJI PAPER CO (JP) 1998-06-03 EP disclosed
US-5612280-A AROMATIC SULFONYLUREA AND SULFONYLTHIOUREA DERIVATIVES AS COLOR DEVELOPERS; COLORFASTNESS, STORAGE STABILITY, WHITENESS NEW OJI PAPER CO., LTD. (JP) 1997-03-18 US disclosed
EP-0604832-A2 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1994-07-06 EP disclosed