Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 4/20 | 0.43 |
| ▸ | ERBB2 | P04626 | 4/20 | 0.43 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3616094 | 0.98 | EGFR (0.42) | EGFRERBB2PLCG1CA2CA1 | |
| SCHEMBL9000869 | 0.98 | EGFR (0.42) | EGFRERBB2PLCG1CA2CA1 | |
| SCHEMBL8474031 | 0.87 | CA2 (0.41) | CA2CA1MMP1MMP2MMP9 | |
| SCHEMBL9200717 | 0.80 | PLCG1 (0.46) | EGFRERBB2PLCG1CA2CA1 | |
| SCHEMBL1138688 | 0.80 | PLCG1 (0.46) | EGFRERBB2PLCG1CA2CA1 | |
| SCHEMBL259654 | 0.78 | CA2 (0.52) | CA2CA1MMP1MMP2MMP9 | |
| SCHEMBL4371994 | 0.78 | ABAT (0.50) | CA2CA1TAAR1IDO1CA12 | |
| SCHEMBL3134989 | 0.77 | TAAR1 (0.46) | EGFRERBB2PLCG1CA2CA1 | |
| SCHEMBL24407431 | 0.76 | IDO1 (0.42) | CA2CA1MMP1MMP2MMP9 | |
| SCHEMBL2336520 | 0.76 | CA1 (0.34) | CA2CA1MMP1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9926327-B2 | Process for preparing 7H-pyrrolo[2,3-D]pyrimidine compounds | ZOETIS SERVICES LLC (US) | 2018-03-27 | — | — | US | claimed |
| US-20250020997-A1 | PHOTORESIST COMPOSITIONS AND METHODS OF MANUFACTURING INTEGRATED CIRCUIT DEVICES USING THE SAME | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2025-01-16 | — | — | US | disclosed |
| EP-3416965-B1 | PROCESS FOR PREPARING 7H-PYRROLO [2,3-D]PYRIMIDINE COMPOUNDS | ZOETIS SERVICES LLC (US) | 2020-10-07 | — | — | EP | disclosed |
| EP-3416965-A1 | PROCESS FOR PREPARING 7H-PYRROLO [2, 3-D]PYRIMIDINE COMPOUNDS | Zoetis Services LLC (US) | 2018-12-26 | — | — | EP | disclosed |
| EP-2976340-B1 | CYCLOALKYL NITRILE PYRAZOLO PYRIDONES AS JANUS KINASE INHIBITORS | MERCK SHARP & DOHME (US) | 2018-06-13 | — | — | EP | disclosed |
| US-9926327-B2 | Process for preparing 7H-pyrrolo[2,3-D]pyrimidine compounds | ZOETIS SERVICES LLC (US) | 2018-03-27 | — | — | US | disclosed |
| US-9926327-B2 | Process for preparing 7H-pyrrolo[2,3-D]pyrimidine compounds | ZOETIS SERVICES LLC (US) | 2018-03-27 | — | — | US | disclosed |
| WO-2017142740-A1 | PROCESS FOR PREPARING 7H-PYRROLO [2, 3-D] PYRIMIDINE COMPOUNDS | ZOETIS SERVICES LLC (US) | 2017-08-24 | — | — | WO | disclosed |
| WO-2017142740-A1 | PROCESS FOR PREPARING 7H-PYRROLO [2, 3-D] PYRIMIDINE COMPOUNDS | ZOETIS SERVICES LLC (US) | 2017-08-24 | — | — | WO | disclosed |
| US-20170233397-A1 | PROCESS FOR PREPARING 7H-PYRROLO[2,3-D]PYRIMIDINE COMPOUNDS | ZOETIS SERVICES LLC | 2017-08-17 | — | — | US | disclosed |
| EP-0708760-A1 | CYCLIC HYDRAZINE COMPOUNDS | Novartis AG (CH) | 1996-05-01 | — | — | EP | disclosed |
| WO-1995002582-A1 | CYCLIC HYDRAZINE COMPOUNDS | CIBA-GEIGY AG (CH) | 1995-01-26 | — | — | WO | disclosed |
| US-5279899-A | Metal coated polyamide having a sulfonate containing compound at interface | MONSANTO COMPANY (US) | 1994-01-18 | — | — | US | disclosed |
| WO-1993019239-A1 | SULFONATED POLYAMIDES | MONSANTO COMPANY (US) | 1993-09-30 | — | — | WO | disclosed |
| US-4598076-A | 2-pyrrolin-3-carbonitril-derivatives, pharmaceutical compositions containing them and their anti-inflammatory and ulcer protective activity | WARNER-LAMBERT COMPANY (US) | 1986-07-01 | — | — | US | disclosed |
| EP-0091045-B1 | 2-PYRROLINE-3-CARBONITRILE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THEM | GÖDECKE AKTIENGESELLSCHAFT (DE) | 1986-02-26 | — | — | EP | disclosed |
| US-4517185-A | 2-Pyrrolin-3-carbonitrile derivatives, and pharmaceutical compositions containing them and their anti-inflammatory and ulcer protective activity | WARNER-LAMBERT COMPANY (US) | 1985-05-14 | — | — | US | disclosed |
| US-4208351-A | Stereoselective preparation of hexahydro dibenzopyranones and intermediates therefor | ELI LILLY AND COMPANY (US) | 1980-06-17 | — | — | US | disclosed |
| US-4176233-A | Stereoselective preparation of hexahydro dibenzopyranones and intermediates therefor | ELI LILLY AND COMPANY (US) | 1979-11-27 | — | — | US | disclosed |
| US-4102902-A | Stereoselective preparation of hexahydro dibenzopyranones and intermediates therefor | ELI LILLY AND COMPANY (US) | 1978-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170233397-A1 | PROCESS FOR PREPARING 7H-PYRROLO[2,3-D]PYRIMIDINE COMPOUNDS | TPMT, TYMS, TYMP | EGFR 4615/4885ERBB2 3586/4885PLCG1 1994/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.