Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLCG1 | P19174 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 6/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 4/20 | 0.40 |
| ▸ | CA9 | Q16790 | 3/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1138688 | 0.84 | PLCG1 (0.46) | PLCG1CA2TAAR1HTR2ACYP2A6 | |
| SCHEMBL9629254 | 0.80 | IDO1 (0.43) | PLCG1CA2TAAR1HTR2ACYP2A6 | |
| SCHEMBL13196 | 0.80 | NPC1 (0.44) | PLCG1CA2TAAR1HTR2ACYP2A6 | |
| SCHEMBL11137088 | 0.80 | CA2 (0.60) | PLCG1CA2TAAR1HTR2ANPC1 | |
| SCHEMBL6466 | 0.80 | EGFR (0.43) | PLCG1CA2TAAR1HTR2ACYP2A6 | |
| SCHEMBL2028261 | 0.80 | PLCG1 (0.43) | PLCG1CA2TAAR1HTR2ACYP2A6 | |
| SCHEMBL9421744 | 0.80 | FAAH (0.60) | PLCG1CA2TAAR1HTR2ACYP2A6 | |
| SCHEMBL9000869 | 0.78 | EGFR (0.42) | PLCG1CA2TAAR1HTR2ANPC1 | |
| SCHEMBL9000871 | 0.78 | PLCG1 (0.46) | PLCG1CA2TAAR1HTR2ANPC1 | |
| SCHEMBL9798010 | 0.78 | CA2 (0.48) | PLCG1CA2TAAR1HTR2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0405436-B1 | Dihetero nitrogen-containing cycloheteroethanoanthracene derivatives as antipsychotic agents | SEARLE & CO (US) | 1995-11-15 | — | — | EP | claimed |