Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.49 |
| ▸ | CES1 | P23141 | 1/20 | 0.49 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.49 |
| ▸ | CTSS | P25774 | 12/20 | 0.45 |
| ▸ | CTSL | P07711 | 4/20 | 0.45 |
| ▸ | CTSB | P07858 | 4/20 | 0.45 |
| ▸ | CTSK | P43235 | 4/20 | 0.45 |
| ▸ | CMA1 | P23946 | 3/20 | 0.45 |
| ▸ | CTSG | P08311 | 1/20 | 0.45 |
| ▸ | PRSS8 | Q16651 | 2/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.41 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.41 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.41 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6466589 | 0.91 | DAGLA (0.56) | FAAHCES1DAGLACTSSCTSL | |
| SCHEMBL6466909 | 0.91 | DAGLA (0.56) | FAAHCES1DAGLACTSSCTSL | |
| SCHEMBL6463429 | 0.87 | DAGLA (0.47) | FAAHCES1DAGLACTSSCTSL | |
| SCHEMBL6465889 | 0.85 | DAGLA (0.52) | FAAHCES1DAGLACTSSCTSL | |
| SCHEMBL7181300 | 0.82 | CTSS (0.47) | FAAHCES1DAGLACTSSCTSL | |
| SCHEMBL7048981 | 0.81 | DAGLA (0.45) | FAAHCES1DAGLACTSSCTSL | |
| SCHEMBL6464884 | 0.81 | CTSS (0.49) | FAAHCES1DAGLACTSSCTSL | |
| SCHEMBL6464305 | 0.80 | KDM4E (0.48) | FAAHCES1DAGLACTSSCTSL | |
| SCHEMBL6465141 | 0.80 | CTSS (0.48) | FAAHCES1DAGLACTSSCTSL | |
| SCHEMBL6463419 | 0.80 | CTSS (0.48) | FAAHCES1DAGLACTSSCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1516877-A1 | Amine derivatives as protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2005-03-23 | — | — | EP | disclosed |