Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 15/20 | 0.47 |
| ▸ | CTSL | P07711 | 2/20 | 0.47 |
| ▸ | CTSB | P07858 | 2/20 | 0.47 |
| ▸ | CTSK | P43235 | 2/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | PRSS8 | Q16651 | 2/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7043343 | 0.91 | CTSS (0.49) | CTSSCTSLCTSBCTSKFAAH | |
| SCHEMBL7046616 | 0.89 | MMP12 (0.47) | CTSSCTSLCTSBCTSKFAAH | |
| SCHEMBL7049727 | 0.87 | CTSS (0.46) | CTSSCTSLCTSBCTSKFAAH | |
| SCHEMBL6466058 | 0.82 | FAAH (0.49) | CTSSCTSLCTSBCTSKFAAH | |
| SCHEMBL6471948 | 0.81 | CTSS (0.50) | CTSSCTSLCTSBCTSKFAAH | |
| SCHEMBL6061690 | 0.81 | CTSS (0.49) | CTSSCTSLCTSBCTSKCYP3A4 | |
| SCHEMBL6462739 | 0.81 | CTSS (0.49) | CTSSCTSLCTSBCTSKCYP3A4 | |
| SCHEMBL7046177 | 0.81 | CTSS (0.49) | CTSSCTSLCTSBCTSKCYP3A4 | |
| SCHEMBL6466909 | 0.77 | DAGLA (0.56) | CTSSCTSLCTSBCTSKFAAH | |
| SCHEMBL6466589 | 0.77 | DAGLA (0.56) | CTSSCTSLCTSBCTSKFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6576630-B1 | Alkanoyl substituted benzooxazoles or naphthooxazoles | AXYS PHARMACEUTICALS, INC. | 2003-06-10 | — | — | US | disclosed |